Table 3 Main pathways identified by profile-1 genes
Ingenuity Canonical Pathways | gene hits | -log (p-value) |
|---|---|---|
Cdc42 | 36 | 14.2 |
Phospholipase C | 42 | 7.13 |
NF-κβ | 33 | 7.92 |
Interleukin-4 | 17 | 4.78 |
LXR/RXR Activation | 15 | 3.63 |
Erythropoietin | 14 | 3.17 |
PPARα/RXRα ± Activation | 21 | 2.19 |
Rac | 16 | 2.17 |
SAPK/JNK | 14 | 1.92 |
p70S6K | 17 | 1.88 |
Acute Phase Response | 21 | 1.66 |
Notch | 7 | 1.64 |
PPAR | 12 | 1.56 |
ERK/MAPK | 21 | 1.44 |
p38 MAPK | 13 | 1.44 |
Insulin Receptor | 16 | 1.43 |