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Figure 2 | BMC Genomics

Figure 2

From: Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma

Figure 2

CoGAPS inferred gene expression patterns. Box plot of six gene expression patterns inferred from the HaCaT gene expression data for samples in Table 1. Plotted values are normalized to sum to one across all samples and are averaged across three applications of the CoGAPS algorithm. All results for HaCaT-EGFRWT are colored in green, HaCaT-HRASVal12D in red, HaCaT-EGFRWT in grey, HaCaT-p65WT in blue, and HaCaT-vector in black. The y-axis is labeled according to the row of the inferred P matrix plotted in each panel. Specifically, (a) contains the pattern attributed to the baseline HaCaT activity, (b) attributed to HaCaT-HRASVal12D, (c) HaCaT-vector control, (d) HaCaT-EGFRWT, (e) serum, and (f) HaCaT-p65WT.

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