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Table 5 NF-κB - family TFBS found in promoter region of human genes

From: The dependence of expression of NF-κB-dependent genes: statistics and evolutionary conservation of control sequences in the promoter and in the 3′ UTR

Gene name Distinct TFBS All TFBS TFBS indexa)
CCL20 (E) 6 22 4.58
CXCL1/Gro-a (E) 4 21  
CXCL2/Gro-b (E) 5 6  
CXCL3/Gro-g (E) 5 15  
EFNA1 (E) 1 1  
IL6 (E) 3 20  
IL8 (E) 1 71  
IRF1 (E) 8 50  
NFKBIA / IkBa (E) 7 44  
PLAU (E) 9 22  
PTGS2 (E) 5 24  
REL (E) 7 42  
TNF (E) 6 25  
TNFAIP3 (E) 6 35  
BCL3 (M) 5 30 3.32
BID (M) 5 6  
BIRC2 (M) 4 10  
CD83 (M) 7 19  
CFB / CompB (M) 7 29  
ECE1 (M) 7 14  
GCH1 (M) 2 4  
GFPT2 (M) 8 34  
IFNGR2 (M) 7 13  
KLRC3 (M) 0 0  
NFKB1/ NF-κB1 (M) 8 37  
NFKBIE / IkBe (M) 6 18  
RELB (M) 4 34  
SDC4 (M) 7 21  
SLC7A2 (M) 1 1  
SOD2 (M) 4 9  
TNFAIP2/ B94 (M) 4 9  
TRAF2 (M) 7 21  
ICAM1 (L) 5 13 3.05
IL27RA (L) 4 13  
IL32 / NK4 (L) 4 8  
NFKB2 (L) 11 29  
PTGES (L) 5 9  
TAP1 (L) 8 19  
TAPBP (L) 5 32  
TNIP1/ Naf-1 (L) 9 28  
TRAF1 (L) 0 0  
TRAF3 (L) 6 20  
TRIM16 (L) 4 15  
  1. Results of search for NF-κB - family TFBS in human promoters in Early, Middle and Late genes. Gene name is presented in first column and affinity to the Early (E), Middle (M) and Late (L) genes group. Second column presents the number of distinct TFBS found across the promoter. Third column presents the number of all sites found using ConSite[13]. Last column presents ratio of average counts of all found motifs to average of distinct motifs per gene in given group of genes, which is called the motif overlap index
  2. a) TFBS motif overlap index