Genome-wide recruitment to Polycomb-modified chromatin and activity regulation of the synovial sarcoma oncogene SYT-SSX2

Table 6 Distribution of SYT-SSX2-overlapping epigenetic markers relative to transcription start sites of downregulated genes

Marker	In	0-5	5-10	10-15	15-20	20-25	25-30	30-35	35-40	40-45	45-50
DNA me	7.27	4.55	0.91	0.91	0	0.91	0.91	0	0	0.91	2.73
H3K4me1	23.6	8.18	9.09	8.18	5.45	3.64	8.18	5.45	3.64	8.18	1.82
H3K4me2	17.3	10.0	3.64	1.82	1.82	3.64	3.64	0	0	4.55	2.73
H3K4me3	17.3	10.9	2.73	3.64	1.82	4.55	2.73	0.91	0.91	3.64	6.64
H3K27me3	22.7	3.64	10.0	7.27	7.27	7.27	12.7	8.18	11.8	15.5	16.4
H3K9Ac	14.6	9.09	4.55	3.64	2.73	1.82	1.82	0	0	2.73	1.82
H3K18Ac	17.3	3.64	7.27	6.36	4.55	2.73	3.64	0	4.55	3.64	3.64
H3K36me3	8.18	0.91	1.82	1.82	0.91	2.73	0.91	0.91	1.82	0	0
H4K12Ac	12.7	9.09	3.64	7.27	1.82	3.64	1.82	0	0	3.64	2.73
H2BUb	7.27	0	1.82	0.91	0	1.82	0	0.91	1.82	0	0.91
PolII	18.2	10.0	3.64	0.91	4.55	2.73	1.82	2.73	0.91	2.73	4.55

Percentages are relative to the total number of downregulated genes with SYT-SSX2 peaks that overlap any epigenetic marker from 0-50kb upstream of the TSS and including the gene body (total = 110). Numbers in first row represent distances measured in kilobases.

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