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Table 4 List of genes involved in the immune response identified between the markers flanking the peaks of the QTL detected

From: A maximum likelihood QTL analysis reveals common genome regions controlling resistance to Salmonella colonization and carrier-state

Chicken chr.1

QTL position

FM2position

Human chr.3

Start (pb)

Gene ID4

Symbol

Description

Ensembl ID5

2

38.06 Mb/ 86 cM

31.78-38.35 Mb

7

32,053,542

777943

MIR148A

microRNA mir-148a

ENSGALG00000018281

7

32,326,549

420629

SKAP2

src kinase associated phosphoprotein 2

ENSGALG00000011051

7

32,584,271

-

gga-mir-1732

microRNA-mir-1732

ENSGALG00000025254

7

32,586,148

777944

MIR196-2

microRNA mir-196-2

ENSGALG00000018282

7

32,879,740

395490

TAX1BP1

Tax1 (human T-cell leukemia virus type I) binding protein 1

ENSGALG00000011123

7

33,469,922

428436

TRIL

TLR4 interactor with leucine-rich repeats

-

7

33,567,743

428437

CHN2

chimerin (chimaerin) 2, involved in Rac signalling

ENSGALG00000011164

3

33,985,086

420640

ANKRD28

ankyrin repeat domain 28 (promotes cell migration)

ENSGALG00000011226

3

34,275,134

395109

RFTN1

raftlin, lipid raft linker 1 (B cell-specific major lipid raft protein)

ENSGALG00000011241

3

34,473,226

420645

PLCL2

phospholipase C-like 2, involved in MAPK pathway and PI3K signalling

ENSGALG00000011248

3

35,783,173

420649

RAB5A

RAB5A, member RAS oncogene family, involve in endocytosis

ENSGALG00000011272

3

37,167,138

420654

NKIRAS1

NFKB inhibitor interacting Ras-like 1

ENSGALG00000011289

19

3.38 Mb/ 21 cM

2.71- 3.80 Mb

1

2,823,176

417489

LAT2/ NTAL_CHICK

Linker for activation of T cells family, member 2

ENSGALG00000001305

17

3,408,203

395930

RABEP1/

RABAPTIN1

rabaptin, RAB GTPase binding effector protein 1

ENSGALG00000001737

23

0.84 Mb/ 1 cM

0.72- 1.32

1

843,249

428208

HIVEP3

Human immunodeficiency virus type I enhancer binding protein 3

ENSGALG00000000635

26

2.95 Mb/ 29 cM

2.60-3.31 Mb

 

2,896,047

-

gga-mir-205a

microRNA-mir-205a

ENSGALG00000018312

1

2,976,923

419862

TRAF3IP3

TRAF3 interacting protein 3, TNF-receptor associated interacting protein

ENSGALG00000001373

1

2,989,458

419863

IRF6

Interferon regulatory factor 6

ENSGALG00000001405

  1. 1 Chicken chromosome.
  2. 2 Flanking markers.
  3. 3 Human chromosome.
  4. 4 Gene identification in NCBI database.
  5. 5 Identification of gene in Ensembl database.