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Table 4 Key genes 1 related to breast muscle development or lipid metabolism in two breeds of chickens

From: Identification of differentially expressed genes and pathways for intramuscular fat deposition in pectoralis major tissues of fast-and slow-growing chickens

Breed

Symbol

Gene

Coefficient

Regulation

Trait

AA

BMP2K

BMP-2-inducible protein kinase

−0.97

-

Breast muscle

 

CAPNS1

Calpain, small subunit 1

1.00

+

 

GDF3

Growth differentiation factor 3

1.00

+

 

CH25H

Cholesterol 25-hydroxylase

0.92

+

PLIP

 

HMGCLL1

3-hydroxymethyl-3-methylglutaryl- Coenzyme A lyase-like 1

0.97 or 0.97

+

TG or IMF

 

NACA

Nascent polypeptide-associated complex alpha subunit

−1.00

-

PLIP

 

RBP7

Retinol binding protein 7

−0.95

-

PLIP

 

RCJMB04

_10b24

membrane bound O-acyltransferase domain containing

1.00

+

PLIP

 

RCJMB04

_13o20

NSFL1 (p97) cofactor (p47)

1.00

+

PLIP

 

SGPL1

Sphingosine-1-phosphate lyase 1

−1.00 or −1.00

-

TG or IMF

 

SH3PXD2B

SH3 and PX domains 2B

−0.95 or −0.96

-

TG or IMF

 

SNX3

Sorting nexin 3

0.96

+

PLIP

 

THBS1

Thrombospondin-1

1.00 or 1.00

+

TG or IMF

 

THRSP

Thyroid hormone responsive, SPOT14 homolog

−0.86 or −0.85

-

TG or IMF

 

UCP3

Uncoupling protein 3

1.00 or 1.00

+

TG or IMF

BJY

ANKRD1

Ankyrin repeat domain 1

0.94

+

Breast muscle

 

CENPF

Centromere protein F

−0.77

-

 

ELN

Elastin

−0.92

-

 

FGF7

Fibroblast growth factor 7

−0.99

-

 

FGFR1

Fibroblast growth factor receptor 1

−0.98

-

 

PLG

Plasminogen

0.96

+

 

MYBL2

V-myb myeloblastosis viral oncogene homolog (avian)-like 2

−0.97

-

 

MYCN

V-myc myelocytomatosis viral related oncogene, neuroblastoma derived

−0.94

-

 

YWHAH

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein

0.99

+

PLIP

 

NR3C2

Nuclear receptor subfamily 3, group C, member 2

0.95

+

PLIP

 

LOC416618

NAD(P) dependent steroid dehydrogenase-like

−0.74

-

PLIP

 

EHHADH

Enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase

0.90 or 0.85

+

TG or IMF

 

ETFDH

Electron-transferring-flavoprotein dehydrogenase

−0.95

-

PLIP

AA/BJY 2

MYBPC1

Myosin binding protein C, slow type

0.96/0.96

+

Breast muscle

 

CETP

Cholesteryl ester transfer protein

0.98/0.80

+

PLIP

 

GLTPD1

Glycolipid transfer protein domain containing 1

−1.00/-0.96

-

PLIP

 

SNX4

Sorting nexin 4

0.95/1.00 or 0.94/0.90

+

TG or IMF

  1. All correlations were significant (p < 0.05 or p < 0.01). 1Key gene were defined as its expression determined by microarray was significantly correlated (p < 0.05 or p < 0.01) with changes in breast muscle weight or in content of IMF, TG or PLTP across the sampled ages. 2Common to both BJY and AA breeds, the expression of genes was significantly correlated with target traits across ages. “+” represents up-regulated effect; “-” represents down-regulated effect. d = day. IMF, Intramuscular fat; TG, Triglyceride; PLIP, Phospholipids; BJY, Beijing-you; AA, Arbor Acres.