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Table 2 Pair-wise comparison of Kolmogorov distances between probe ratio distributions of unamplified and amplified Normal patient DNA samples

From: Characterization of whole genome amplified (WGA) DNA for use in genotyping assay development

Sample

Kolmogorov distance

Normal UnAmp/UnAmp

Replicate 1

Replicate 2

Replicate 3

Replicate 4

NormalAmp-R/ UnAmp

Replicate 1

0.398

0.402

0.405

0.402

 

Replicate 2

0.409

0.413

0.416

0.413

Replicate 3

0.385

0.389

0.392

0.388

Replicate 4

0.415

0.419

0.423

0.420

Normal Amp-G/UnAmp

Replicate 1

0.370

0.354

0.386

0.342

 

Replicate 2

0.381

0.366

0.398

0.354

Replicate 3

0.357

0.340

0.373

0.328

Replicate 4

0.388

0.373

0.405

0.361

  1. Each row represents probe ratio distributions from replications of amplified DNA samples; each column represents probe ratio distributions from replications of unamplified DNA samples. The median values are 0.407 and 0.368 for REPLI-g and GenomiPhi, respectively. UnAmp (unamplified samples); Amp-R (REPLI-g amplified samples); Amp-G (GenomiPhi amplified samples).
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BMC Genomics

ISSN: 1471-2164

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