Larval midgut modifications associated with Bti resistance in the yellow fever mosquito using proteomic and transcriptomic approaches

Table 1 Lethal concentrations and resistance ratio for the LiTOX and susceptible strains for Bti and Cry toxins

Toxins	Strain	LC₅₀in ng/mL (95% CI)	RR₅₀
Cry4Aa	Susceptible	646.28 (514.20–826.93)	/
	LiTOX	43873.12 (28396.11–78207.31)	67.9 fold
Cry4Ba	Susceptible	322.27 (228.39–468.57)	/
	LiTOX	2922.26 (1924.95–4168.76)	9.1 fold
Cry11Aa	Susceptible	156.14 (112.86–219.46)	/
	LiTOX	1434.81 (1146.52–1774.22)	9.2 fold
Bti Vectobac WG	Susceptible	90.6 (79.89–101.12)	/
	LiTOX	312.6 (277.27–359.49)	3.5 fold

Lethal concentrations 50% (LC ₅₀ ) of the resistant (LiTOX) and the susceptible strain for the three Cry toxins (Cry4Aa, Cry4Ba and Cry11Aa) and for the commercial Bti at 24 h. Resistance ratios 50 (RR ₅₀ ) are calculated for each product as LC ₅₀ of LiTOX divided by LC ₅₀ of Bora- Bora strain. LC ₅₀ are expressed in ng/mL.

ISSN: 1471-2164