|
Essential genes
|
|
Rv0336
|
-
|
Conserved 13E12 repeat family protein
|
71.2
|
+
|
[25]
|
|
Rv0405
|
pks6
|
Probable membrane bound polyketide synthase
|
26.7
|
+
|
[26]
|
|
Rv1371
|
-
|
Probable conserved membrane protein
|
17.8
|
+
|
[29]
|
|
Rv1469
|
ctpD
|
Probable cation transporter P-type ATPase D
|
2.5
|
+
|
[29]
|
|
Rv1477
|
ripA
|
Peptidoglycan hydrolase
|
72.9
|
+
|
[28, 30]
|
|
Rv1753c
|
PPE24
|
PPE Family protein
|
2.4
|
+
|
[26],[25][27]
|
|
Rv1978
|
-
|
Conserved hypothetical protein
|
41.8
|
+
|
[27]
|
|
Rv2388c
|
hemN
|
Coproporphyrinogen III oxidase
|
28.7
|
-
|
[29],[27]
|
|
Rv2708c
|
-
|
Conserved hypothetical protein
|
61.8
|
+
|
[27]
|
|
Rv2808
|
-
|
Hypothetical protein
|
23.6
|
+
|
[29]
|
|
Rv2812
|
-
|
Probable transposase
|
8.8
|
+
|
[28, 30]
|
|
Rv2817c
|
-
|
Conserved hypothetical protein
|
71.8
|
+
|
[28, 30]
|
|
Rv3018c
|
PPE46
|
PPE family protein
|
4.7
|
+
|
[28, 30]
|
|
Rv3112
|
moaD1
|
Probable molybdenum cofactor biosynthesis protein D
|
29.8
|
+
|
[28, 30]
|
|
Rv3113
|
-
|
Possible phosphatase
|
34.1
|
+
|
[28, 30]
|
|
Rv3114
|
-
|
Conserved hypothetical protein
|
40.7
|
-
|
[29]
|
|
Rv3201c
|
-
|
Probable ATP-dependent DNA helicase
|
0.2
|
+
|
[28, 30]
|
|
Rv3229c
|
desA3
|
Possible linoleoyl-CoA desaturase
|
43.4
|
+
|
[29],[27]
|
|
Rv3343c
|
PPE54
|
PPE family protein
|
9.3
|
+
|
[28, 30]
|
|
Rv3376
|
-
|
Conserved hypothetical protein
|
60.9
|
+
|
[27]
|
|
Essential genes - Less probable to affect function
|
|
Rv0001
|
dnaA
|
Chromosomal replication initiation protein
|
95.1
|
+
|
[28, 30]
|
|
Rv0755c
|
PPE12
|
PPE Family protein
|
96.4
|
+
|
[28, 30]
|
|
Rv2282c
|
-
|
Probable transcription regulator (LysR family)
|
84.9
|
+
|
[27]
|
|
Rv2833c
|
ugpB
|
Probable Sn-glycerol-3-phosphate-binding lipoprotein
|
88.9
|
+
|
[28, 30]
|
|
Rv2856
|
nicT
|
Possible nickel-transport integral membrane protein
|
89.8
|
+
|
[28, 30]
|
|
Rv3111
|
moaC1
|
Molybdenum cofactor biosynthesis protein C
|
92.8
|
-
|
[28, 30]
|
|
Rv3177
|
-
|
Possible peroxidase
|
90.4
|
+
|
[28, 30]
|
|
Virulence, detoxification and adaptation category (Tuberculist)
|
|
Rv0591
|
mce2C
|
MCE-family protein
|
56.1
| | |
|
Rv1477
|
ripA
|
Peptidoglycan hydrolase
|
72.9
| | |
|
Rv1720c
|
vapC12
|
Possible toxin
|
7.9
| | |
|
Rv2494
|
-
|
Conserved hypothetical protein
|
97.2
| | |
|
Rv3176c
|
mesT
|
Probable epoxide hydrolase
|
11.8
| | |
|
Rv3177
|
-
|
Possible peroxidase
|
90.4
| | |
|
Rv3473c (MT3579
|
bpoA
|
Possible peroxidase
|
93.8
| | |
