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Table 6 Expression cluster enrichment analysis

From: Divergent gene expression in the conserved dauer stage of the nematodes Pristionchus pacificus and Caenorhabditis elegans

Expression clusters over-represented in "dauer enriched" and "exit enriched genes" in C. elegans and P. pacificus

Expression clusters related to dauer larvae, stress response and starvation / feeding

Sl.No.

Expression Cluster

cel_dauer

cel_exit

ppa_dauer

ppa_exit

1

Wang_Kim_WBPaper00005859_DauerEnriched

10.45

0

0

0

2

Wang_Kim_WBPaper00005859_EarlyGenes

0

5.99

0

10.67

3

Wang_Kim_WBPaper00005859_ClimbingGenes

0

14.58

0

4.62

4

Wang_Kim_WBPaper00005859_LateGenes

0

63.09

0

0

5

WBPaper00024393:strongly_regulated_dauer_genes_UP

1.39

0

0

0

6

WBPaper00024393:strongly_regulated_dauer_genes_DOWN

0

8.49

0

10.85

7

WBPaper00034757:up_by_oxidative_stress

4.2

0

0

0

8

WBPaper00034757:down_by_oxidative_stress

0

6.47

0

6.82

9

WBPaper00035227:heat_shock_regulated

9.74

0

0

0

10

WBPaper00035873:dpy-10_regulated

0

25.06

0

3.89

11

WBPaper00035873:dpy-9_regulated

0

2.02

0

1.57

12

WBPaper00035873:osm-11_regulated

0

2.02

0

1.57

13

WBPaper00035873:osm-7_regulated

0

2.4

0

2.07

14

WBPaper00035873:osm-8_regulated

0

42.83

0

4.45

15

WBPaper00035873:osmotically_regulated

0

0

0

4.65

16

WBPaper00032948:StarveUp2

6.17

0

2.5

0

17

WBPaper00032948:StarveUp3

7.15

0

0

0

18

WBPaper00032948:StarveUp4

10.45

0

0

0

19

WBPaper00032948:FedUp

0

78.95

0

5.12

20

WBPaper00032948:MoltOssilate

0

74.78

0

0

21

WBPaper00032062:age_regulated_genes

0

5.37

0

4.75

Expression clusters related to to pathogen response, RNAi machinery etc.

Sl.No.

Expression Cluster

cel_dauer

cel_exit

ppa_dauer

ppa_exit

22

WBPaper00028482:PA14_upregulate

0

0

0

2.03

23

WBPaper00028789:PA14_vs_gacA_downregulated_4hr

0

5.9

0

0

24

WBPaper00028789:PA14_vs_gacA_downregulated_8hr

0

6.7

0

0

25

WBPaper00028789:PA14_vs_OP50_downregulated_8hr

0

6.85

0

1.81

26

WBPaper00028789:PA14_vs_OP50_upregulated_4hr

0

0

0

1.4

27

WBPaper00028789:PA14_vs_OP50_upregulated_8hr

0

0

0

2.02

28

WBPaper00030985:Enterococcus_faecalis_upregulated

0

0

0

1.6

29

WBPaper00028789:pmk-1_downregulated

0

0

0

1.46

30

WBPaper00029437:dcr-1_upregulated

3.13

0

0

0

31

WBPaper00029437:rde-4_upregulated

0

0

0

1.69

32

WBPaper00027111:eri-1(mg366)_downregulated

0

2.23

0

0

33

WBPaper00027111:rde-3(r459)_upregulated

0

0

0

1.52

34

WBPaper00035892:KIM5_regulated

0

0

0

4.79

35

WBPaper00035892:KIM5_vs_OP50_Up

0

0

0

2.36

Tissue specific, and other expression clusters

Sl.No.

Expression Cluster

cel_dauer

cel_exit

ppa_dauer

ppa_exit

36

WBPaper00030839:Embryo_Pan_Neuronal

0

0

6.67

0

37

WBPaper00030839:Larval_Pan_Neuronal

4.75

0

2.71

0

38

WBPaper00031003:0hr_muscle_depleted

0

2.99

0

0

39

WBPaper00031003:24hr_muscle_depleted

0

2.11

0

2.73

40

WBPaper00031003:total_muscle_depleted

0

2.29

0

0

41

WBPaper00031003:total_muscle_enriched

0

0

2.42

0

42

WBPaper00031532:Larva_Pan_Neuronal_Depleted

0

28.03

0

11.41

43

WBPaper00031532:Larva_Pan_Neuronal_Enriched

2.48

0

4.69

0

44

WBPaper00026980:intestine_enriched

0

0

3.46

1.5

45

WBPaper00024671:AFD_AWB_vs_unsorted_downregulated

0

3.02

0

3.59

46

WBPaper00031832:slr-2_regulated

0

0

0

2.75

47

WBPaper00033101:spr-5_regulated

0

6.44

0

0

48

WBPaper00034739:N2lessDR1350

0

39.13

0

0

49

WBPaper00034739:RIL17lessRIL14

0

18.11

0

0

50

WBPaper00035905:FBF-1_Associated

0

0

5.54

0

51

WBPaper00037611:RNP-8-associated

0

0

4.92

0

52

WBPaper00025032:PAL-1_target_genes

0

2.58

0

0

  1. This table lists - log10 transformed p-values of tests for enrichment of dauer and dauer-exit genes from both species for 52 out of 169 expression clusters. These 52 expression clusters passed the FDR corrected p-value threshold of 0.05 for at least one condition. The overlap between dauer enriched clusters and dauer-exit enriched clusters is statistically significant (Fisher’s exact test p-values = 0.0185 and 6.833E-06 respectively).