| |
Transcription/Translation/RNA processing
| | |
|
FOXF1
|
forkhead box F1
|
2294
|
2.0
|
|
NFKB2
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
|
4791
|
2.0
|
|
NR6A1
|
nuclear receptor subfamily 6, group A, member 1
|
2649
|
2.0
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
1052
|
2.1
|
|
ETV5
|
ets variant 5
|
2119
|
2.1
|
|
FST
|
follistatin
|
10468
|
2.2
|
|
KLF6
|
Kruppel-like factor 6
|
1316
|
2.2
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
1052
|
2.3
|
|
EGR3
|
early growth response 3
|
1960
|
2.3
|
|
SAMD4A
|
sterile alpha motif domain containing 4A
|
23034
|
2.3
|
|
ELL2
|
elongation factor, RNA polymerase II, 2
|
22936
|
2.4
|
|
HIVEP2
|
human immunodeficiency virus type I enhancer binding protein 2
|
3097
|
2.4
|
|
MAFB
|
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
|
9935
|
2.4
|
|
FOSL2
|
FOS-like antigen 2
|
2355
|
2.5
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
3398
|
2.5
|
|
KLF2
|
Kruppel-like factor 2 (lung)
|
10365
|
2.5
|
|
RELB
|
v-rel reticuloendotheliosis viral oncogene homolog B
|
5971
|
2.5
|
|
MAFF
|
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
|
23764
|
2.8
|
|
LARP6
|
La ribonucleoprotein domain family, member 6
|
55323
|
3.1
|
|
REL
|
v-rel reticuloendotheliosis viral oncogene homolog (avian)
|
5966
|
3.1
|
|
FOSB
|
FBJ murine osteosarcoma viral oncogene homolog B
|
2354
|
3.2
|
|
HES1
|
hairy and enhancer of split 1 (Drosophila)
|
3280
|
3.2
|
|
SOD2
|
superoxide dismutase 2, mitochondrial
|
6648
|
3.4
|
|
ATF3
|
activating transcription factor 3
|
467
|
3.6
|
|
FOSL1
|
FOS-like antigen 1
|
8061
|
4.1
|
|
ZFP36
|
zinc finger protein 36, C3H type, homolog (mouse)
|
7538
|
4.2
|
|
ZNF331
|
zinc finger protein 331
|
55422
|
4.4
|
|
BACH2
|
BTB and CNC homology 1, basic leucine zipper transcription factor 2
|
60468
|
4.4
|
|
NFKBIE
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
|
4794
|
4.4
|
|
EGR1
|
early growth response 1
|
1958
|
6.2
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2353
|
8.4
|
|
NR4A2
|
nuclear receptor subfamily 4, group A, member 2
|
4929
|
10.9
|
| |
Signal Transduction
| | |
|
EDN2
|
endothelin 2
|
1907
|
2.0
|
|
EPHA2
|
EPH receptor A2
|
1969
|
2.1
|
|
RIT1
|
Ras-like without CAAX 1
|
6016
|
2.1
|
|
SH2D3A
|
SH2 domain containing 3A
|
10045
|
2.1
|
|
KLRC1
|
killer cell lectin-like receptor subfamily C, member 1///killer cell lectin-like receptor subfamily C, member 2
|
3821
|
2.2
|
|
PSD4
|
pleckstrin and Sec7 domain containing 4
|
23550
|
2.5
|
|
ADM
|
adrenomedullin
|
133
|
2.7
|
|
GPRC5C
|
G-protein-coupled receptor, family C, group 5, member C
|
55890
|
2.7
|
|
BDKRB2
|
bradykinin receptor B2
|
624
|
2.8
|
|
GDF15
|
growth differentiation factor 15
|
9518
|
3.0
|
|
GPR87
|
G protein-coupled receptor 87
|
53836
|
3.4
|
|
RASA4
|
RAS p21 protein activator 4///RAS p21 protein activator 4 pseudogene
|
10156
|
8.8
|
|
GEM
|
GTP binding protein overexpressed in skeletal muscle
|
2669
|
14.1
|
|
GABBR1
|
gamma-aminobutyric acid (GABA) B receptor, 1///ubiquitin D
|
10537
|
24.5
|
|
RRAD
|
Ras-related associated with diabetes
|
6236
|
115.2
|
| |
Inflammatory response/Immune response
| | |
|
KLRC1
|
killer cell lectin-like receptor subfamily C, member 1
|
3821
|
2.2
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
5743
|
2.3
|
|
CCL22
|
chemokine (C-C motif) ligand 22
|
6367
|
3.0
|
|
IL6R
|
interleukin 6 receptor
|
3570
|
3.0
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
10318
|
3.2
|
|
EBI3
|
Epstein-Barr virus induced 3
|
10148
|
3.2
|
|
IL27RA
|
interleukin 27 receptor, alpha
|
9466
|
3.5
|
|
TRIM22
|
tripartite motif-containing 22
|
10346
|
3.8
|
|
IL32
|
interleukin 32
|
9235
|
3.8
|
|
TNFAIP6
|
tumor necrosis factor, alpha-induced protein 6
|
7130
|
4.0
|
|
GBP2
|
guanylate binding protein 2, interferon-inducible
|
2634
|
5.2
|
|
GBP2
|
guanylate binding protein 2, interferon-inducible
|
2634
|
5.4
|
|
CCL19
|
chemokine (C-C motif) ligand 19
|
6363
|
6.2
|
|
CXCL1
|
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
|
2919
|
11.7
|
|
CXCL11
|
chemokine (C-X-C motif) ligand 11
|
6373
|
13.1
|
|
CXCL3
|
chemokine (C-X-C motif) ligand 3
|
2921
|
19.1
|
|
CCL20
|
chemokine (C-C motif) ligand 20
|
6364
|
20.1
|
|
PTX3
|
pentraxin-related gene, rapidly induced by IL-1 beta
|
5806
|
81.1
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2920
|
87.0
|
| |
Apoptosis regulation
| | |
|
ZMAT3
|
zinc finger, matrin type 3
|
64393
|
2.0
|
|
JMJD6
|
jumonji domain containing 6
|
23210
|
2.0
|
|
AEN
|
apoptosis enhancing nuclease
|
64782
|
2.1
|
|
ADORA2A
|
adenosine A2a receptor
|
135
|
2.2
|
|
CD70
|
CD70 molecule
|
970
|
2.2
|
|
FAS
|
Fas (TNF receptor superfamily, member 6)
|
355
|
2.3
|
|
BAG3
|
BCL2-associated athanogene 3
|
9531
|
2.4
|
|
BIK
|
BCL2-interacting killer (apoptosis-inducing)
|
638
|
2.4
|
|
BCL6
|
B-cell CLL/lymphoma 6
|
604
|
2.7
|
|
TNFRSF1B
|
tumor necrosis factor receptor superfamily, member 1B
|
7133
|
3.3
|
|
ZC3H12A
|
zinc finger CCCH-type containing 12A
|
80149
|
4.1
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
4792
|
5.2
|
|
NR4A1
|
nuclear receptor subfamily 4, group A, member 1
|
3164
|
5.4
|
|
IER3
|
immediate early response 3
|
8870
|
5.7
|
|
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3
|
7128
|
6.4
|
|
BTG2
|
BTG family, member 2
|
7832
|
7.0
|
|
TNFRSF9
|
tumor necrosis factor receptor superfamily, member 9
|
3604
|
8.2
|
|
BIRC3
|
baculoviral IAP repeat-containing 3
|
330
|
14.8
|
|
IL6
|
interleukin 6 (interferon, beta 2)
|
3569
|
18.0
|
| |
Cell cycle regulation
| | |
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
1647
|
2.2
|
|
RGS2
|
regulator of G-protein signaling 2, 24 kDa
|
5997
|
2.2
|
|
MAP3K8
|
mitogen-activated protein kinase kinase kinase 8
|
1326
|
2.3
|
|
SESN1
|
sestrin 1
|
27244
|
2.6
|
|
CDKN1A
|
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
|
1026
|
2.8
|
|
CYLD
|
cylindromatosis (turban tumor syndrome)
|
1540
|
2.9
|
|
PLK2
|
polo-like kinase 2 (Drosophila)
|
10769
|
3.0
|
|
SMAD3
|
SMAD family member 3
|
4088
|
4.4
|
|
JUN
|
jun oncogene
|
3725
|
4.6
|
|
GADD45B
|
growth arrest and DNA-damage-inducible, beta
|
4616
|
4.8
|
|
DUSP1
|
dual specificity phosphatase 1
|
1843
|
8.5
|
|
IL8
|
interleukin 8
|
3576
|
41.7
|
| |
Regulation of cell growth/Regulation of cell proliferation
| | |
|
ZMAT3
|
zinc finger, matrin type 3
|
64393
|
2.0
|
|
CSF1
|
colony stimulating factor 1 (macrophage)
|
1435
|
2.1
|
|
FGFR2
|
fibroblast growth factor receptor 2
|
2263
|
2.1
|
|
ABTB2
|
ankyrin repeat and BTB (POZ) domain containing 2
|
25841
|
2.4
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
8835
|
2.4
|
|
PGF
|
placental growth factor
|
5228
|
2.6
|
|
HBEGF
|
heparin-binding EGF-like growth factor
|
1839
|
2.7
|
|
LIF
|
leukemia inhibitory factor (cholinergic differentiation factor)
|
3976
|
2.9
|
|
FGF18
|
fibroblast growth factor 18
|
8817
|
4.9
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
6347
|
6.7
|
|
IL11
|
interleukin 11
|
3589
|
7.4
|
|
RARRES1
|
retinoic acid receptor responder (tazarotene induced) 1
|
5918
|
7.5
|
|
IGFBP1
|
insulin-like growth factor binding protein 1
|
3484
|
32.2
|
|
DLGAP4
|
discs, large (Drosophila) homolog-associated protein 4
|
22839
|
2.5
|
|
EFNA1
|
ephrin-A1
|
1942
|
2.5
|
|
WNT4
|
wingless-type MMTV integration site family, member 4
|
54361
|
9.3
|
| |
Cell adhesion
| | |
|
LYPD3
|
LY6/PLAUR domain containing 3
|
27076
|
2.0
|
|
PDZD2
|
PDZ domain containing 2
|
23037
|
2.1
|
|
FERMT2
|
fermitin family homolog 2 (Drosophila)
|
10979
|
2.2
|
|
NINJ1
|
ninjurin 1
|
4814
|
2.2
|
|
SIRPA
|
signal-regulatory protein alpha
|
140885
|
2.2
|
|
COL7A1
|
collagen, type VII, alpha 1
|
1294
|
2.3
|
|
LAMB3
|
laminin, beta 3
|
3914
|
2.6
|
|
CDH5
|
cadherin 5, type 2 (vascular endothelium)
|
1003
|
4.4
|
|
CTGF
|
connective tissue growth factor
|
1490
|
4.4
|
|
SAA1
|
serum amyloid A1///serum amyloid A2
|
6288
|
10.3
|
|
ICAM1
|
intercellular adhesion molecule 1
|
3383
|
10.8
|
| |
Transport
| | |
|
SLC37A1
|
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
|
54020
|
2.0
|
|
SLC1A3
|
solute carrier family 1 (glial high affinity glutamate transporter), member 3
|
6507
|
2.2
|
|
C19orf28
|
chromosome 19 open reading frame 28
|
126321
|
2.6
|
|
NPTX1
|
neuronal pentraxin I
|
4884
|
2.6
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
11182
|
3.5
|
|
HBA1
|
hemoglobin, alpha 1
|
3039
|
5.4
|
| |
Metabolic process
| | |
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)
|
3157
|
2.0
|
|
PTGS1
|
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
|
5742
|
2.0
|
|
IDS
|
iduronate 2-sulfatase
|
3423
|
2.2
|
|
PI4K2A
|
phosphatidylinositol 4-kinase type 2 alpha
|
55361
|
2.2
|
|
PLA2G4C
|
phospholipase A2, group IVC (cytosolic, calcium-independent)
|
8605
|
2.2
|
|
C12orf5
|
chromosome 12 open reading frame 5
|
57103
|
2.3
|
|
PANX1
|
pannexin 1
|
24145
|
2.3
|
|
ABCA1
|
ATP-binding cassette, subfamily A (ABC1), member 1
|
19
|
2.4
|
|
AMPD3
|
adenosine monophosphate deaminase (isoform E)
|
272
|
2.4
|
|
SAT1
|
spermidine/spermine N1-acetyltransferase 1
|
6303
|
2.5
|
|
AKR1B1
|
aldo-keto reductase family 1, member B1 (aldose reductase)
|
231
|
2.6
|
|
GCNT3
|
glucosaminyl (N-acetyl) transferase 3, mucin type
|
9245
|
2.6
|
|
PITPNM1
|
phosphatidylinositol transfer protein, membrane-associated 1
|
9600
|
2.6
|
|
MICAL2
|
microtubule-associated monoxygenase, calponin and LIM domain containing 2
|
9645
|
3.2
|
|
PPAP2B
|
phosphatidic acid phosphatase type 2B
|
8613
|
3.2
|
|
ARG2
|
arginase, type II
|
384
|
4.1
|
|
PTGES
|
prostaglandin E synthase
|
9536
|
4.7
|
|
GFPT2
|
glutamine-fructose-6-phosphate transaminase 2
|
9945
|
5.0
|
| |
Phosphorylation/Dephosphorylation
| | |
|
DUSP6
|
dual specificity phosphatase 6
|
1848
|
2.0
|
|
FAM129A
|
family with sequence similarity 129, member A
|
116496
|
2.3
|
|
DUSP13
|
dual specificity phosphatase 13
|
51207
|
2.6
|
|
DUSP5
|
dual specificity phosphatase 5
|
1847
|
4.1
|
|
PTPRE
|
protein tyrosine phosphatase, receptor type, E
|
5791
|
4.1
|
| |
Response to stress
| | |
|
HSPA2
|
heat shock 70 kDa protein 2
|
3306
|
2.3
|
|
HSPA1A
|
heat shock 70 kDa protein 1A
|
3303
|
2.9
|
|
HSPB8
|
heat shock 22 kDa protein 8
|
26353
|
3.1
|
|
HSPB3
|
heat shock 27 kDa protein 3
|
8988
|
4.0
|
|
HSPB7
|
heat shock 27 kDa protein family, member 7 (cardiovascular)
|
27129
|
4.0
|
|
DNAJB1
|
DnaJ (Hsp40) homolog, subfamily B, member 1
|
3337
|
4.2
|
|
HSPA6
|
heat shock 70 kDa protein 6
|
3310
|
7.6
|
| |
Ubiquitin
| | |
|
ENC1
|
ectodermal-neural cortex (with BTB-like domain)
|
8507
|
2.3
|
|
MAP1LC3C
|
microtubule-associated protein 1 light chain 3 gamma
|
440738
|
3.4
|
| |
Others/Unknown
| | |
|
OLR1
|
oxidized low density lipoprotein (lectin-like) receptor 1
|
4973
|
2.0
|
|
TRIB1
|
tribbles homolog 1 (Drosophila)
|
10221
|
2.0
|
|
UNC13A
|
unc-13 homolog A (C. elegans)
|
23025
|
2.0
|
|
SNAI1
|
snail homolog 1 (Drosophila)
|
6615
|
2.1
|
|
FSTL3
|
follistatin-like 3 (secreted glycoprotein)
|
10272
|
2.2
|
|
GAB2
|
GRB2-associated binding protein 2
|
9846
|
2.2
|
|
PDLIM3
|
PDZ and LIM domain 3
|
27295
|
2.2
|
|
PMEPA1
|
prostate transmembrane protein, androgen induced 1
|
56937
|
2.2
|
|
SLC1A3
|
solute carrier family 1 (glial high affinity glutamate transporter), member 3
|
6507
|
2.2
|
|
FNDC3B
|
fibronectin type III domain containing 3B
|
64778
|
2.3
|
|
PHLDA3
|
pleckstrin homology-like domain, family A, member 3
|
23612
|
2.3
|
|
SLC25A4
|
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
|
291
|
2.3
|
|
TPM4
|
tropomyosin 4
|
7171
|
2.3
|
|
DSE
|
dermatan sulfate epimerase
|
29940
|
2.5
|
|
VEGFC
|
vascular endothelial growth factor C
|
7424
|
2.5
|
|
CSTA
|
cystatin A (stefin A)
|
1475
|
2.6
|
|
ZDHHC18
|
zinc finger, DHHC-type containing 18
|
84243
|
2.6
|
|
CDK2AP2
|
cyclin-dependent kinase 2 associated protein 2
|
10263
|
2.7
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
25976
|
2.7
|
|
CSTA
|
cystatin A (stefin A)
|
1475
|
2.8
|
|
TNFAIP2
|
tumor necrosis factor, alpha-induced protein 2
|
7127
|
2.8
|
|
PSD4
|
pleckstrin and Sec7 domain containing 4
|
23550
|
3.1
|
|
KRT17
|
keratin 17
|
3872
|
3.7
|
|
ARC
|
activity-regulated cytoskeleton-associated protein
|
23237
|
5.4
|
|
LXN
|
latexin
|
56925
|
5.5
|
|
TRIM31
|
tripartite motif-containing 31
|
11074
|
20.1
|
