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Table 1 The upward effect of JTX on the gene expression in the large intestine in IQI SPF mice

From: Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade

SPFLI-up      
Probe Set ID Gene Name Gene Symbol Entre ID Fold Change p-value
93956_at interferon-induced protein with tetratricopeptide repeats 3 Ifit3 15959 4.71 0.092
95024_at ubiquitin specific peptidase 18 Usp18 24110 4.50 0.020
98822_at ISG15 ubiquitin-like modifier G1p2 53606 4.06 0.077
100981_at interferon-induced protein with tetratricopeptide repeats 1 Ifit1 15957 3.84 0.033
103066_at thymidylate kinase family LPS-inducible member Tyki 22169 3.72 0.012
103639_at interferon-induced protein with tetratricopeptide repeats 2 Ifit2 15958 3.37 0.036
104669_at interferon regulatory factor 7 Irf7 54123 2.87 0.069
98410_at interferon inducible GTPase 2 Iigp2 54396 2.49 0.021
104177_at radical S-adenosyl methionine domain containing 2 Rsad2 58185 2.45 0.033
103335_at lectin, galactose binding, soluble 9 Lgals9 16859 2.40 0.038
93442_at zinc finger protein 316 Zfp316 54201 1.97 0.065
161357_r_at glutathione S-transferase, mu 2 Gstm2 14863 1.90 0.049
102867_at TEA domain family member 4 Tead4 21679 1.82 0.009
100909_at protease, serine, 8 (prostasin) Prss8 76560 1.81 0.066
103657_i_at metal response element binding transcription factor 2 Mtf2 17765 1.73 0.081
102879_s_at Fc receptor, IgG, high affinity I Fcgr1 14129 1.71 0.053
92560_g_at vascular cell adhesion molecule 1 Vcam1 22329 1.69 0.036
95037_at cyclin-dependent kinase 9 (CDC2-related kinase) Cdk9 107951 1.69 0.086
104708_at Transducin (beta)-like 1 X-linked Tbl1x 21372 1.67 0.082
103884_at ATP binding domain 1 family, member C Atpbd1c 68080 1.66 0.061
99446_at membrane-spanning 4-domains, subfamily A, member 1 Ms4a1 12482 1.63 0.083
103634_at interferon dependent positive acting transcription factor 3 gamma Isgf3g 16391 1.58 0.068
93464_at A kinase (PRKA) anchor protein (yotiao) 9 Akap9 100986 1.54 0.088
92384_at xeroderma pigmentosum, complementation group A Xpa 22590 1.54 0.051
100472_at enabled homolog (Drosophila) Enah 13800 1.52 0.067
103080_at SAM domain and HD domain, 1 Samhd1 56045 1.51 0.045
102808_at Sodium channel, voltage-gated, type I, beta Scn1b 20266 1.51 0.074
  1. The genes whose change was > 1.50 fold, with p < 0.1 (n = 3, Welch's t test) were the listed sorted by fold-change. Unidentified 8 probe sets were omitted from the list. The genes appeared commonly in Tables 1 and 2 were in bold letters.
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BMC Genomics

ISSN: 1471-2164

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