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Table 1 The upward effect of JTX on the gene expression in the large intestine in IQI SPF mice

From: Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade

SPFLI-up

     

Probe Set ID

Gene Name

Gene Symbol

Entre ID

Fold Change

p-value

93956_at

interferon-induced protein with tetratricopeptide repeats 3

Ifit3

15959

4.71

0.092

95024_at

ubiquitin specific peptidase 18

Usp18

24110

4.50

0.020

98822_at

ISG15 ubiquitin-like modifier

G1p2

53606

4.06

0.077

100981_at

interferon-induced protein with tetratricopeptide repeats 1

Ifit1

15957

3.84

0.033

103066_at

thymidylate kinase family LPS-inducible member

Tyki

22169

3.72

0.012

103639_at

interferon-induced protein with tetratricopeptide repeats 2

Ifit2

15958

3.37

0.036

104669_at

interferon regulatory factor 7

Irf7

54123

2.87

0.069

98410_at

interferon inducible GTPase 2

Iigp2

54396

2.49

0.021

104177_at

radical S-adenosyl methionine domain containing 2

Rsad2

58185

2.45

0.033

103335_at

lectin, galactose binding, soluble 9

Lgals9

16859

2.40

0.038

93442_at

zinc finger protein 316

Zfp316

54201

1.97

0.065

161357_r_at

glutathione S-transferase, mu 2

Gstm2

14863

1.90

0.049

102867_at

TEA domain family member 4

Tead4

21679

1.82

0.009

100909_at

protease, serine, 8 (prostasin)

Prss8

76560

1.81

0.066

103657_i_at

metal response element binding transcription factor 2

Mtf2

17765

1.73

0.081

102879_s_at

Fc receptor, IgG, high affinity I

Fcgr1

14129

1.71

0.053

92560_g_at

vascular cell adhesion molecule 1

Vcam1

22329

1.69

0.036

95037_at

cyclin-dependent kinase 9 (CDC2-related kinase)

Cdk9

107951

1.69

0.086

104708_at

Transducin (beta)-like 1 X-linked

Tbl1x

21372

1.67

0.082

103884_at

ATP binding domain 1 family, member C

Atpbd1c

68080

1.66

0.061

99446_at

membrane-spanning 4-domains, subfamily A, member 1

Ms4a1

12482

1.63

0.083

103634_at

interferon dependent positive acting transcription factor 3 gamma

Isgf3g

16391

1.58

0.068

93464_at

A kinase (PRKA) anchor protein (yotiao) 9

Akap9

100986

1.54

0.088

92384_at

xeroderma pigmentosum, complementation group A

Xpa

22590

1.54

0.051

100472_at

enabled homolog (Drosophila)

Enah

13800

1.52

0.067

103080_at

SAM domain and HD domain, 1

Samhd1

56045

1.51

0.045

102808_at

Sodium channel, voltage-gated, type I, beta

Scn1b

20266

1.51

0.074

  1. The genes whose change was > 1.50 fold, with p < 0.1 (n = 3, Welch's t test) were the listed sorted by fold-change. Unidentified 8 probe sets were omitted from the list. The genes appeared commonly in Tables 1 and 2 were in bold letters.
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BMC Genomics

ISSN: 1471-2164

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