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Table 2 The downward effect of JTX on the gene expression in the large intestine in Balb/c SPF mice

From: Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade

BALBLI-down

    

Probe Set ID

Gene Name

Gene Symbol

Entre ID

Fold Change

p-value

160841_at

D site albumin promoter binding protein

Dbp

13170

0.27

0.029201

104177_at

radical S-adenosyl methionine domain containing 2

Rsad2

58185

0.39

0.012171

95024_at

ubiquitin specific peptidase 18

Usp18

24110

0.41

0.016077

160933_at

interferon gamma induced GTPase

Igtp

16145

0.46

0.052323

100981_at

interferon-induced protein with tetratricopeptide repeats 1

Ifit1

15957

0.48

0.030177

98822_at

ISG15 ubiquitin-like modifier

G1p2

53606

0.49

0.053022

103202_at

guanylate nucleotide binding protein 4

Gbp4

55932

0.52

0.018878

98410_at

interferon inducible GTPase 2

Iigp2

54396

0.55

0.008083

93956_at

interferon-induced protein with tetratricopeptide repeats 3

Ifit3

15959

0.56

0.053353

103634_at

interferon dependent positive acting transcription factor 3 gamma

Isgf3g

16391

0.56

0.009681

101561_at

metallothionein 2

Mt2

17750

0.59

0.001359

93573_at

metallothionein 1

Mt1

17748

0.61

0.00141

161964_r_at

Protein kinase C, zeta

Prkcz

18762

0.61

0.066851

103335_at

lectin, galactose binding, soluble 9

Lgals9

16859

0.62

0.024207

99076_at

Nuclear receptor subfamily 1, group D, member 2

Nr1d2

353187

0.63

0.049119

93085_at

proteosome (prosome, macropain) subunit, beta type 9

Psmb9

16912

0.63

0.00915

160208_at

splicing factor 3b, subunit 3

Sf3b3

101943

0.63

0.043591

104750_at

interferon gamma inducible protein 47

Ifi47

15953

0.64

0.053488

161287_f_at

MYB binding protein (P160) 1a

Mybbp1a

18432

0.64

0.014332

93178_at

neuronal guanine nucleotide exchange factor

Ngef

53972

0.65

0.017146

92315_at

schlafen 4

Slfn4

20558

0.65

0.053414

104669_at

interferon regulatory factor 7

Irf7

54123

0.67

0.017792

  1. The genes whose change was < 0.67 fold, with p < 0.1 (n = 3, Welch's t test) were the listed sorted by fold-change. Unidentified 4 probe sets were omitted from the list "BALBLI-down", respectively. The genes appeared commonly in Tables 1 and 2 were in bold letters.
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BMC Genomics

ISSN: 1471-2164

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