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Table 2 The downward effect of JTX on the gene expression in the large intestine in Balb/c SPF mice

From: Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade

BALBLI-down     
Probe Set ID Gene Name Gene Symbol Entre ID Fold Change p-value
160841_at D site albumin promoter binding protein Dbp 13170 0.27 0.029201
104177_at radical S-adenosyl methionine domain containing 2 Rsad2 58185 0.39 0.012171
95024_at ubiquitin specific peptidase 18 Usp18 24110 0.41 0.016077
160933_at interferon gamma induced GTPase Igtp 16145 0.46 0.052323
100981_at interferon-induced protein with tetratricopeptide repeats 1 Ifit1 15957 0.48 0.030177
98822_at ISG15 ubiquitin-like modifier G1p2 53606 0.49 0.053022
103202_at guanylate nucleotide binding protein 4 Gbp4 55932 0.52 0.018878
98410_at interferon inducible GTPase 2 Iigp2 54396 0.55 0.008083
93956_at interferon-induced protein with tetratricopeptide repeats 3 Ifit3 15959 0.56 0.053353
103634_at interferon dependent positive acting transcription factor 3 gamma Isgf3g 16391 0.56 0.009681
101561_at metallothionein 2 Mt2 17750 0.59 0.001359
93573_at metallothionein 1 Mt1 17748 0.61 0.00141
161964_r_at Protein kinase C, zeta Prkcz 18762 0.61 0.066851
103335_at lectin, galactose binding, soluble 9 Lgals9 16859 0.62 0.024207
99076_at Nuclear receptor subfamily 1, group D, member 2 Nr1d2 353187 0.63 0.049119
93085_at proteosome (prosome, macropain) subunit, beta type 9 Psmb9 16912 0.63 0.00915
160208_at splicing factor 3b, subunit 3 Sf3b3 101943 0.63 0.043591
104750_at interferon gamma inducible protein 47 Ifi47 15953 0.64 0.053488
161287_f_at MYB binding protein (P160) 1a Mybbp1a 18432 0.64 0.014332
93178_at neuronal guanine nucleotide exchange factor Ngef 53972 0.65 0.017146
92315_at schlafen 4 Slfn4 20558 0.65 0.053414
104669_at interferon regulatory factor 7 Irf7 54123 0.67 0.017792
  1. The genes whose change was < 0.67 fold, with p < 0.1 (n = 3, Welch's t test) were the listed sorted by fold-change. Unidentified 4 probe sets were omitted from the list "BALBLI-down", respectively. The genes appeared commonly in Tables 1 and 2 were in bold letters.
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BMC Genomics

ISSN: 1471-2164

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