Skip to main content

Table 1 Funspec classification into biological process categories of genes up- or downregulated in response to changes in the oxidation of NADPH and NADH

From: A comparative transcriptomic, fluxomic and metabolomic analysis of the response of Saccharomyces cerevisiae to increases in NADPH oxidation

  NADH-Bdh 200 mM NADPH-Bdh 100 mM NADPH-Bdh 200 mM NADPH-Bdh 300 mM
f     
Upregulated genes     
10 alcoholic metabolic bioprocess GO:0006066
  BDH1 ADH7 BDH1 BDH1 ADH7 BDH1 ADH7
196 response to stress GO:0006950
   PAU24 PAU14 PAU1 PAU7 PAU24 PAU3 PAU10 PAU2 PAU11 PAU12 PAU13 PAU14 PAU15 PAU1 PAU17 PAU18 PAU23 PAU4 PAU6 MET22 PAU20 FRT1 PAU7 PAU2 PAU14 PAU17 PAU4 MET22 ZEO1 PAU20
511 translation GO:0006412
    RPL31A RPS16B RPS17B RPL27B RPL23B RPL30 RPL24A RPL24B RPL40B RLP24 RPS31 RPS25B RPS22B RPS17A RPL15B RPL9B RPS3 RPS19A RPL25 RPS28A RPL20B RPL33A  
41 methionine biosynthetic process GO:0009086
  MET10 MET17   MET6 MET3 MET14 MET17 MET22 MET16 MET6 MET10 MET5 MET14 MET17 MET22 MET16
10 L-serine biosynthetic process GO:0006564
    SER3 SER3 SER33
12 lysine biosynthetic process GO:0009085
    LYS12 LYS9 LYS12 LYS9
  hydrogen sulfide biosynthetic process GO:0070814
     CYS4
561 oxidation reduction GO:0055114
  BDH1 ADH7 MET10 ARI1 ERG3 AHP1 AAD15    BDH1 ADH7 AAD3 YDR541C SER3 MET10 ARI1 GND1 SER33 LYS12 MET5 MDH1 LYS9 AAD15 IDH2 MET16
10 pentose-phosphate shunt GO:0006098
    SOL3 GND1 SOL3 GND1 TAL1 TKL1
19 cofactor metabolic process GO:0051186
     MDH1 IDH2
9 glucose catabolic process to ethanol GO:0019655
  PDC5    
Downregulated genes     
8 fermentation GO:0006113
  ADH4   ADH4 ADH4
129 vacuolar protein catabolic process GO:0007039
     PEX29 HXK1 STF2 TFS1 PGM2 DDR48 GPH1
9 glucose catabolic process to ethanol GO:0019655
     PDC1 PDC5
322 translational elongation GO:0006414
    ZRT1 PRY1 TPO1 AGA1 WHI5 PDR12 SAM3 THI2 ZRT1 QDR2 PRY1 IZH2 WHI5 PDR12 SAM3
103 carbohydrate metabolic process GO:0005975
     EMI2 HXK1 PGM2 GPH1