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Table 6 Novel baboon miRNAs categorized by diet and LDL-C. The numbers of predicted target genes, and the 2-7mer seed region for each novel miRNA, are shown

From: Differential microRNA response to a high-cholesterol, high-fat diet in livers of low and high LDL-C baboons

Chow diet
High LDL-C Low LDL-C
‘Seed’ No. of targets ‘Seed’ No. of targets
GGGTGCG 37 ACCTCGA 6
TAAGAAC 423 TGGAATA 315
TGGACGT 8 TTATAAT 826
TTGACTA 111   
Total unique targets 561 Total unique targets 1079
HCHF diet
High LDL-C Low LDL-C
‘Seed’ No. of targets ‘Seed’ No. of targets
CCCAAAT 306 TTCTGAT 441
CCCGCGG 6 TGGACGT 8
AGAGCTT 575 GCGCTGG 15
TTTTGCT 149   
ACCTCGA 6   
CTACCCC 59   
CTGTGAG 14   
Total unique targets 902 Total unique targets 416
Both diets
High LDL-C Low LDL-C
‘Seed’ No. of targets ‘Seed’ No. of targets
ATCAAGG 147 ATCAAGG 147
CCGCCCT 14 CCGCCCT 14
TTTTTGC 349 CAGGCAC 402
CAGGCAC 402   
TTGTTGC 179   
Total unique targets 985 Total unique targets 552