A microRNA activity map of human mesenchymal tumors: connections to oncogenic pathways; an integrative transcriptomic study

Table 3 Example of a potential miRNA sequence alteration

hsa-miR-422a ACUGGACUUAGGGUCAGAAGGC
Sample	Sequencing Reads	Counts (≤1 Bases Different)	Counts (0 Bases Different)
LEIO_1	ACUGGACUU - GGGUCAGAAGGC	10	0
LEIO_2	ACUGGACUU - GGGUCAGAAGGC	15	0
LIPO_1	ACUGGACUU - GGGUCAGAAGGC	25	0
LIPO_2	ACUGGACUU - GGGUCAGAAGGC	15	0

The reference mature sequence of miR-422a is shown along with RNA-sequencing reads for each duplicate of one leiomyosarcoma (LEIO) and one liposarcoma (LIPO). The column denoted by " ≤ 1 bases different" reports the number of sequencing reads when allowing for a single base difference in mapping to the reference. The column denoted by "0 bases different" reports sequencing reads when allowing for no differences in mapping to the reference.

ISSN: 1471-2164