Table 2 Large families of putative secreted proteins with ‘domains of unknown function’
From: A survey of putative secreted and transmembrane proteins encoded in the C. elegans genome
Family | No of genes | Upregulated upon infectionb | Size range (aa) | Typical domain organization | |
|---|---|---|---|---|---|
DUF23 | 65 (42) | 10 | 400-600 | bah-1 |
|
nsp-genes | 58 (41) | 25 | 35-100 | nspd-3 |
|
DUF19 | 51 (42) | 14 | 140-220 | C17B7.4 |
|
nlp-genes | 44 (41) | 25 | 60-180 | nlp-1 |
|
DUF130 | 41 (25) | 1 | 140-230 | F43C11.2 |
|
DUF13 | 35 (15) | 4 | 200-350 | C13A2.4 |
|
DUF148 | 32 (31) | 9 | 150-250 | C32H11.5 |
|
flp-genes | 30 (28) | 4 | 66-170 | flp-4 |
|
CW | 28 (21) | 0 | 230-330 | F32D8.2 |
|
DUF274 | 22 (15) | 20 | 340-470 | F54E2.1 |
|
small DB proteins | 18 (17) | 11 | 130-260 | F26G1.9 |
|
DUF229 | 15 (11) | 4 | 400-700 | F32D8.2 |
|
DUF263 | 13 (11) | 3 | 260-560 | R13D7.2 |
|
DUF1647 | 14 (11) | 3 | 340-410 | T15D6.9 |
|
DUF236 | 13 (10) | 0 | 200-320 | F27C1.3 |
|
TF352284c | 13 (13) | 6 | 120-160 | F17E9.2 |
|
DUF316 | 12 (10) | 1 | 300-750 | R01H2.2 |
|
DUF273 | 12 (7) | 0 | 300-400 | F31F4.1 |
|
DUF271 | 11 (7) | 0 | 350-400 | F28G4.4 |
|
DUF268 | 11 (9) | 0 | 310-380 | K04A8.1 |
|
DUF870 | 11 (8) | 3 | 100-200 | ZC239.22 |
|
DUF672 | 10 (7) | 0 | 270-340 | R05A10.8 |
|
DUF1261 | 10 (10) | 9 | 220-270 | F56C9.7 |
|
TF319413c | 10 (8) | 7 | 123-135 | K02E11.5 |
|
