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Figure 2 | BMC Genomics

Figure 2

From: A microarray analysis of gnotobiotic mice indicating that microbial exposure during the neonatal period plays an essential role in immune system development

Figure 2

Venn diagram showing differential expression of genes in the LI, SI, LIV, and SPL of 0WexGF vs. GF, 5WexGF vs. GF, and SPF vs. GF mice. Upper row: The numbers of probe sets differentially expressed (p < 0.05). A total of 1498 probes sets were differentially expressed in the LI, 2711 in the SI, 274 in the LIV, and 1805 in the SPL. The greatest number of differentially-expressed probe sets (2188) was observed for SPF mouse SI. Only 22 ~ 36 probe sets were specifically co-regulated in all 3 comparisons in each tissue. Bottom row: The numbers of the GO BP categories having integrated p values of less than 0.05 are shown. In the LI, of the 38 overrepresented categories, 31 were specific for 0WexGF mice. In the SI, 202 of the 204 categories were specific for SPF mice. In the SPL, 160 of the 170 categories were specific for 5WexGF mice. No GO BP categories were overrepresented in the LIV.

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