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Table 3 Top 25 GO categories overrepresented in SPL of 5WexGF mice compared with GF mice

From: A microarray analysis of gnotobiotic mice indicating that microbial exposure during the neonatal period plays an essential role in immune system development

GOID Term Number of Probes p_int
GO:0007507 heart development 91 1.98E-13
GO:0006952 defense response 63 4.39E-12
GO:0016192 vesicle-mediated transport 76 3.47E-11
GO:0015992 proton transport 64 1.69E-09
GO:0001764 neuron migration 32 2.46E-09
GO:0007283 Spermatogenesis 94 2.65E-09
GO:0006816 calcium ion transport 41 3.52E-09
GO:0030036 actin cytoskeleton organization and biogenesis 52 3.81E-09
GO:0042127 regulation of cell proliferation 46 8.17E-09
GO:0016055 Wnt receptor signaling pathway 61 1.16E-08
GO:0007010 cytoskeleton organization and biogenesis 43 1.52E-08
GO:0016337 cell-cell adhesion 33 2.30E-08
GO:0018108 peptidyl-tyrosine phosphorylation 25 2.51E-08
GO:0008610 lipid biosynthetic process 76 2.69E-08
GO:0009987 cellular process 78 3.52E-08
GO:0006954 inflammatory response 48 4.44E-08
GO:0006874 cellular calcium ion homeostasis 23 6.93E-08
GO:0007166 cell surface receptor linked signal transduction 54 9.30E-08
GO:0005975 carbohydrate metabolic process 81 1.01E-07
GO:0016311 Dephosphorylation 61 1.76E-07
GO:0042981 regulation of apoptosis 83 2.21E-07
GO:0007420 brain development 30 3.64E-07
GO:0006935 Chemotaxis 45 4.40E-07
GO:0001701 in utero embryonic development 55 5.95E-07
GO:0009408 response to heat 26 8.93E-07
  1. MGP analysis was performed on GO BP categories which contains 4 ~ 99 genes (“Number of Probes”). The categories were sorted according to the integrated p value (p_int) and top 25 are represented.