Skip to main content

Table 1 C. thermocellum proteins different between ethanol treatment and control

From: Clostridium thermocellum ATCC27405 transcriptomic, metabolomic and proteomic profiles after ethanol stress

Gene

Product

Protein relative fold change (Treatment/Control)

Array relative fold change (Treatment/Control)

Proteomics p-value

Array p-value

Array Sig Index

Cthe_0042

small GTP-binding protein

1.8

1.6

5.0E-03

1.1E-02

1

Cthe_0076

hypothetical protein

1.5

1.2

5.0E-02

3.3E-01

0

Cthe_0087

maf protein

0.04

0.9

2.0E-02

3.2E-01

0

Cthe_0129

metal dependent phosphohydrolase

0.58

1.3

4.0E-03

9.1E-07

1

Cthe_0196

glutamine synthetase, catalytic region

2.4

2.5

2.0E-05

3.0E-11

1

Cthe_0197

glutamine amidotransferase, class-II

38

4.3

4.0E-07

1.5E-14

1

Cthe_0198

Glutamate synthase (NADPH)

7.6

4.1

1.0E-02

3.5E-14

1

Cthe_0200

FAD-dependent pyridine nucleotide-disulphide oxidoreductase

46

1.4

2.0E-02

3.4E-05

1

Cthe_0266

methyl-accepting chemotaxis sensory transducer

0.66

1

2.0E-02

9.8E-01

0

Cthe_0362

transcriptional regulator, AsnC family

0.64

1

7.0E-03

7.8E-01

0

Cthe_0363

aminotransferase, class I and II

0.64

0.9

9.0E-03

4.9E-01

0

Cthe_0395

RbsD or FucU transport

0.02

0.8

2.0E-02

1.9E-02

1

Cthe_0402

copper amine oxidase-like protein

1.6

1.3

2.0E-03

1.3E-03

1

Cthe_0550

heat shock protein Hsp90

0.62

1.1

2.0E-02

6.9E-01

0

Cthe_0559

single-strand binding protein/Primosomal replication protein n

0.33

1.1

2.0E-02

3.0E-01

0

Cthe_0567

peptide deformylase

0.59

1.3

2.0E-02

3.1E-04

1

Cthe_0626

hypothetical protein

0.62

1.1

2.0E-02

1.9E-02

1

Cthe_0681

IMP dehydrogenase/GMP reductase

0.63

1

2.0E-02

3.4E-01

0

Cthe_0715

Adenosylmethionine decarboxylase

0.02

0.5

4.0E-04

7.6E-04

1

Cthe_0849

3-dehydroquinate dehydratase, type II

4.6

2

3.0E-02

3.1E-16

1

Cthe_0902

3-methyl-2-oxobutanoate hydroxymethyltransferase

1.7

1.2

2.0E-03

2.7E-03

1

Cthe_0904

protein-export membrane protein SecD

0.62

0.8

2.0E-02

1.8E-04

1

Cthe_0949

carbamoyl-phosphate synthase, large subunit

1.8

0.7

2.0E-04

1.3E-07

1

Cthe_0951

orotidine 5'-phosphate decarboxylase

1.8

0.7

1.0E-02

1.8E-04

1

Cthe_0953

aspartate carbamoyltransferase

1.9

0.6

1.0E-02

2.0E-02

1

Cthe_0954

Uracil phosphoribosyltransferase

1.5

0.9

4.0E-02

3.5E-02

0

Cthe_0961

aspartate-semialdehyde dehydrogenase

1.8

1.2

3.0E-04

1.1E-03

1

Cthe_1102

fimbrial assembly protein

0.35

1.1

3.0E-02

2.3E-01

0

Cthe_1104

prepilin-type cleavage/methylation

0.61

1

2.0E-02

7.8E-01

0

Cthe_1165

YbbR-like protein

0.49

0.8

6.0E-03

9.5E-02

0

Cthe_1178

isochorismatase hydrolase

1.7

1.6

1.0E-02

1.3E-02

1

Cthe_1212

hypothetical protein

1.8

0.7

9.0E-03

1.0E-05

1

Cthe_1222

RNA methyltransferase, TrmH family, group 3

2.7

1.2

3.0E-02

4.8E-01

0

Cthe_1286

peptidase S1 and S6, chymotrypsin/Hap

2.1

1.1

2.0E-03

6.6E-02

0

Cthe_1326

small GTP-binding protein

0.48

1.1

8.0E-03

2.2E-01

0

Cthe_1329

putative CoA-substrate-specific enzyme activase

0.62

0.9

5.0E-03

1.9E-01

0

Cthe_1350

single-strand binding protein

0.49

0.6

2.0E-02

1.8E-05

1

Cthe_1383

Tetratricopeptide TPR_2

7

0.9

5.0E-03

4.2E-02

0

Cthe_1391

2-isopropylmalate synthase

2.4

0.6

3.0E-03

7.1E-17

1

Cthe_1433

short-chain dehydrogenase/reductase SDR

1.7

1

5.0E-03

3.0E-01

0

Cthe_1539

glutamine synthetase, catalytic region

2.4

3.7

4.0E-03

1.5E-25

1

Cthe_1556

binding-protein-dependent transport systems inner membrane component

0.26

1.2

4.0E-02

1.1E-04

1

Cthe_1570

extracellular solute-binding protein, family 3

0.59

1.6

1.0E-02

7.1E-05

1

Cthe_1605

phosphate ABC transporter (binding protein)-like protein

1.7

1.1

6.0E-03

7.1E-01

0

Cthe_1773

peptidase S16, lon-like protein

0.14

1

6.0E-03

9.3E-01

0

Cthe_1778

copper amine oxidase-like protein

5.1

1.5

2.0E-02

7.1E-03

1

Cthe_1801

ABC transporter related protein

1.9

0.5

8.0E-03

5.0E-15

1

Cthe_1823

Extracellular ligand-binding receptor

49

6.2

1.0E-07

2.5E-28

1

Cthe_1844

transcriptional regulator, BadM/Rrf2 family

0.22

1.2

3.0E-02

1.8E-03

1

Cthe_1911

Carbohydrate binding family 6

2.1

1.1

4.0E-02

1.9E-01

0

Cthe_1912

copper amine oxidase-like protein

1.6

0.9

2.0E-02

6.0E-01

0

Cthe_1922

hypothetical protein

1.7

1.1

5.0E-02

6.9E-01

0

Cthe_1955

RNA binding S1

0.6

1

4.0E-02

7.1E-01

0

Cthe_2095

hydrolase, TatD family

1.6

0.7

5.0E-02

6.8E-07

1

Cthe_2166

putative PAS/PAC sensor protein

0.2

0.7

1.0E-02

2.1E-08

1

Cthe_2171

type III restriction enzyme, res subunit

0.62

1.5

6.0E-03

6.6E-07

1

Cthe_2333

two component transcriptional regulator, winged helix family

0.55

0.9

3.0E-02

4.9E-01

0

Cthe_2403

4-diphosphocytidyl-2 C-methyl-D-erythritol kinase

0.65

1.4

2.0E-02

2.4E-08

1

Cthe_2423

hypothetical protein

2.9

0.9

1.0E-03

7.6E-01

0

Cthe_2424

copper amine oxidase-like protein

3.3

1

6.0E-03

8.9E-01

0

Cthe_2517

acetolactate synthase, small subunit

0.62

0.9

3.0E-02

2.0E-02

1

Cthe_2531

sulfate ABC transporter, periplasmic sulfate-binding protein

1.6

4.4

2.0E-02

1.0E-11

1

Cthe_2706

ABC transporter related protein

1.5

1.2

3.0E-02

4.3E-02

0

Cthe_2819

methyl-accepting chemotaxis sensory transducer

0.21

0.7

2.0E-02

7.2E-06

1

Cthe_2875

sigma 54 modulation protein/ribosomal protein S30EA

1.5

1

9.0E-03

7.9E-01

0

Cthe_2880

histidyl-tRNA synthetase

2.5

1.1

3.0E-03

8.1E-01

0

Cthe_2882

Histidinol dehydrogenase

1.7

0.8

1.0E-02

4.1E-02

0

Cthe_2883

histidinol-phosphate aminotransferase

1.9

0.8

2.0E-04

1.4E-02

1

Cthe_2889

phosphoribosyl-AMP cyclohydrolase

1.8

1.1

1.0E-02

3.2E-01

0

Cthe_2907

ribosomal protein S19

0.65

0.8

3.0E-02

2.5E-02

0

Cthe_3062

signal transduction histidine kinase regulating citrate/malate metabolism

0.63

0.8

3.0E-02

5.4E-03

1

Cthe_3076

Radical SAM

0.45

0.9

8.0E-03

4.7E-01

0

Cthe_3100

Diaminopimelate epimerase

1.6

3.3

1.0E-02

2.1E-07

1

Cthe_3101

aminotransferase, class I and II

1.8

2.2

2.0E-02

3.7E-06

1

Cthe_3107

Radical SAM

0.59

1.4

4.0E-02

2.0E-02

1

Cthe_3157

pyruvate carboxyltransferase

1.5

1.9

3.0E-03

3.0E-17

1

Cthe_3183

TrkA-N

0.04

0.9

2.0E-02

3.6E-01

0

  1. Array significance determined by p-value (p < 0.05) and a significant array different is represented by a 1 in the Array Sig Index column and a 0 is not considered significantly different for a given gene at this time point comparison.