Table 2 Selected differentially expressed genes in S. hygroscopicus 5008 at 37°C compared with at 30°C
Description | Gene ID or name | Fold change |
|---|---|---|
Up-regulated genes at 37°C |  |  |
Validamycin biosynthesis | valABCD, valKLMN, valEF, valIJ | 4.1-23.8 |
PKS-NRPS biosynthesis | SHJG0303-SHJG0325 | 6.8-707.3 |
PKS-NRPS biosynthesis | SHJG1907-SHJG1918, SHJG1921-SHJG1929 | 2.1-11.8 |
Type III PKS biosynthesis | SHJG8479 | 12.9 |
Central carbon metabolisms | SHJG3123 (gntK), SHJG3510 (citE) | 4.6-5.2 |
Nitrogen metabolism | SHJG7666 (gdhA), SHJG7685 (glnA3) | 2.7-3.0 |
Ribosomal proteins | SHJG0705-SHJG0706, SHJG0835-SHJG0836, SHJG2929, SHJG5163-SHJG5164, SHJG5778, SHJG5809-SHJG5816 | 2.1-3.6 |
Heat shock proteins | SHJG4359 (hspX) , SHJG5369-SHJG5372 (dnaK-grpE-dnaJ-hspR), SHJG7073, SHJG8393 | 3.3-5.3 |
Markedly expressed regulators | SHJG0301, SHJG0319, SHJG0322, SHJG0477, SHJG6588, SHJG6678, SHJG6961, SHJG7352 | 4.3-128.2 |
Down-regulated genes at 37°C |  |  |
Glycolysis | SHJG2653 (pfk), SHJG3403 (gap), SHJG3488 (pyk) | 2.6-3.5 |
Nitrogen metabolism | SHJG2665 (ureD), SHJG2667 (ureE), SHJG2668-SHJG2670 (ureCBA) , SHJG3687 (glnA), SHJG3702 (glnII) , SHJG3730 (glnA2), SHJG3958 (nirB) , SHJG4429 (narK) , SHJG4923 (glnR), SHJG6704 (amtB) , SHJG6705 (glnB) , SHJG6706 (glnD) | 4.1-16.7 |
Phosphate starvation response | SHJG0329 (phoA), SHJG2705, SHJG4290 (ppe), SHJG4865 (phoU), SHJG4934 (ppk), SHJG4942-SHJG4945 (pstBACS), SHJG5998-SHJG5999 (neuAB), SHJG8008 (glpQ), SHJG8009 | 3.9-144.3 |
Sulfate assimilation | SHJG1828-SHJG1830, SHJG4909 (cysA), SHJG7116, SHJG7181-SHJG7183 (ssuABC), SHJG7184-SHJG7187 (cysCNDH), SHJG7188, SHJG7189 (cycI) | 4.7-16.8 |
Markedly expressed regulators | SHJG0180, SHJG1204, SHJG1557, SHJG4402, SHJG4865, SHJG5108, SHJG5332, SHJG6822, SHJG7752, SHJG8626, SHJG8650,SHJG8654, SHJG8656, SHJG8657 | 4.3-31.3 |