Figure 5
From: Balancing noise and plasticity in eukaryotic gene expression
Noise plasticity coupling is modulated by genomic neighborhood and distinguishes four control strategies overall. A). A cartoon depicting the different genomic structures (bipromoter, parallel, divergent) upstream of coding genes is shown in ascending order of proximal nucleosome occupancy, plasticity and noise (which coincide). For each structure, we show the average intergenic distance in blue. In red is shown the Spearman ρ coefficient for the observed noise-plasticity correlation. We also show the percent within each class of a given upstream structure , e.g., HNHP mostly exhibit parallel/divergent coding (C) and divergent non-coding (NC) transcripts. B) Four regulatory strategies broadly adjust the noise-plasticity coupling. These strategies emphasize the alternative transcriptional- or translational-based modes of balancing noise and plasticity in yeast.