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Table 1 List of 31 genes selected as a radiosensitivity signature from four microarray platforms

From: Identification of a radiosensitivity signature using integrative metaanalysis of published microarray data for NCI-60 cancer cells

Symbol Description Location Expression in radiosensitive cell
ACTN1 actinin, alpha 1 Cytoplasm Down (0.42)
ANXA2 annexin A2 Plasma Membrane Down (0.36)
ANXA5 annexin A5 Plasma Membrane Down (0.42)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta Cytoplasm Up (−0.49)
CAPNS1 calpain, small subunit 1 Cytoplasm Down (0.48)
CBR1 carbonyl reductase 1 Cytoplasm Down (0.41)
CCND1 cyclin D1 Nucleus Down (0.54)
CD63 CD63 molecule Plasma Membrane Down (0.51)
CORO1A coronin, actin binding protein, 1A Cytoplasm Up (−0.46)
CXCR4 chemokine (C-X-C motif) receptor 4 Plasma Membrane Up (−0.46)
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) Plasma Membrane Down (0.60)
EMP2 epithelial membrane protein 2 Plasma Membrane Down (0.41)
HCLS1 hematopoietic cell-specific Lyn substrate 1 Nucleus Up (−0.58)
HTRA1 HtrA serine peptidase 1 Extracellular Space Down (0.52)
ITGB5 integrin, beta 5 Plasma Membrane Down (0.47)
LAPTM5 lysosomal protein transmembrane 5 Plasma Membrane Up (−0.50)
LRMP lymphoid-restricted membrane protein Cytoplasm Up (−0.49)
MYB v-myb myeloblastosis viral oncogene homolog (avian) Nucleus Up (−0.59)
PFN2 profilin 2 Cytoplasm Down (0.61)
PIR pirin (iron-binding nuclear protein) Nucleus Down (0.43)
PKM2 pyruvate kinase, muscle Cytoplasm Down (0.44)
PTMS parathymosin Nucleus Down (0.48)
PTPRC protein tyrosine phosphatase, receptor type, C Plasma Membrane Up (−0.55)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein Plasma Membrane Up (−0.49)
PYGB phosphorylase, glycogen; brain unknown Down (0.35)
RAB13 RAB13, member RAS oncogene family Plasma Membrane Down (0.43)
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)   
   Cytoplasm Down (0.47)
SCRN1 secernin 1 Cytoplasm Down (0.40)
SQSTM1 sequestosome 1 Cytoplasm Down (0.48)
TWF1 twinfilin, actin-binding protein, homolog 1 (Drosophila) Cytoplasm Down (0.43)
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) Cytoplasm Up (−0.60)
  1. “Down” refers to decreased expression observed in radiosensitive cells relative to radioresistant cells, determined as the slope of the correlation coefficient. “Up” refers to increased expression in radiosensitive cells.