Table 1 List of 31 genes selected as a radiosensitivity signature from four microarray platforms
Symbol | Description | Location | Expression in radiosensitive cell |
|---|---|---|---|
ACTN1 | actinin, alpha 1 | Cytoplasm | Down (0.42) |
ANXA2 | annexin A2 | Plasma Membrane | Down (0.36) |
ANXA5 | annexin A5 | Plasma Membrane | Down (0.42) |
ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | Cytoplasm | Up (−0.49) |
CAPNS1 | calpain, small subunit 1 | Cytoplasm | Down (0.48) |
CBR1 | carbonyl reductase 1 | Cytoplasm | Down (0.41) |
CCND1 | cyclin D1 | Nucleus | Down (0.54) |
CD63 | CD63 molecule | Plasma Membrane | Down (0.51) |
CORO1A | coronin, actin binding protein, 1A | Cytoplasm | Up (−0.46) |
CXCR4 | chemokine (C-X-C motif) receptor 4 | Plasma Membrane | Up (−0.46) |
DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | Plasma Membrane | Down (0.60) |
EMP2 | epithelial membrane protein 2 | Plasma Membrane | Down (0.41) |
HCLS1 | hematopoietic cell-specific Lyn substrate 1 | Nucleus | Up (−0.58) |
HTRA1 | HtrA serine peptidase 1 | Extracellular Space | Down (0.52) |
ITGB5 | integrin, beta 5 | Plasma Membrane | Down (0.47) |
LAPTM5 | lysosomal protein transmembrane 5 | Plasma Membrane | Up (−0.50) |
LRMP | lymphoid-restricted membrane protein | Cytoplasm | Up (−0.49) |
MYB | v-myb myeloblastosis viral oncogene homolog (avian) | Nucleus | Up (−0.59) |
PFN2 | profilin 2 | Cytoplasm | Down (0.61) |
PIR | pirin (iron-binding nuclear protein) | Nucleus | Down (0.43) |
PKM2 | pyruvate kinase, muscle | Cytoplasm | Down (0.44) |
PTMS | parathymosin | Nucleus | Down (0.48) |
PTPRC | protein tyrosine phosphatase, receptor type, C | Plasma Membrane | Up (−0.55) |
PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein | Plasma Membrane | Up (−0.49) |
PYGB | phosphorylase, glycogen; brain | unknown | Down (0.35) |
RAB13 | RAB13, member RAS oncogene family | Plasma Membrane | Down (0.43) |
RALB | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | ||
Cytoplasm | Down (0.47) | ||
SCRN1 | secernin 1 | Cytoplasm | Down (0.40) |
SQSTM1 | sequestosome 1 | Cytoplasm | Down (0.48) |
TWF1 | twinfilin, actin-binding protein, homolog 1 (Drosophila) | Cytoplasm | Down (0.43) |
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | Cytoplasm | Up (−0.60) |