Table 1 Novel miRNAs discovered in B-cells, their chromosome location, mature sequence, and putative folding structure
From: Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing
Temporary name | Genomic location | Mature sequence | Fold |
|---|---|---|---|
sRNA1 | chr11:95714237–95714346 || chr11:41380469- 41380478 | ATCCCACCACTGCCACCA |
|
sRNA2 | chr11:46193225-46193334 | TATCCCGGACGAGCCCCCA |
|
sRNA3 | chr1:218470812-218470921 | CATGTGGGCTAGTTTCAGACAGGT |
|
sRNA4 | chr15:81221792–81221896 || chr15:545116- 545175 | AAGGTAGATAGAACAGGTCTTG |
|
sRNA5 | chr17:76874327-76874436 | ACCTTGGCTCTAGACTGCTTACT |
|
sRNA6 | chr17:24191370-24191479 | GCTCTGACTTTATTGCACTACT |
|
sRNA7 | chr9:78376641-78376750 | CGCTAAACCATTCGTAGACGACCTGCTTC |
|
sRNA8 | chr11:121147952–121148061 || chr11:13287835- 13287776 | GGCTGGTCCGAAGGTAGTGAGT |
|
-
Base-pair probabilities:
- Novel miRNA were predicted using the mirDeep package. The pre-miRNA sequence of sRNA1 and sRNA5 were present in two genomic locations where miRNA have not been previously predicted. The fold column was generated from mFold[30].
