Table 2 Representative IsomiRs detected in B-cells
From: Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing
| miRNA | Sequence | % Control | % Centenarian |
|---|---|---|---|
| hsa-miR-21 | TAGCTTATCAGACTGATGTTGAC | 53.8% | 52.0% |
| TAGCTTATCAGACTGATGTTGA | 43.3% | 44.9% | |
| TAGCTTATCAGACTGATGTTGAA | 2.7% | 2.8% | |
| TAGCTTATCAGACTGATGTTGAT | 0.2% | 0.3% | |
| hsa-miR-193b | AACTGGCCCTCAAAGTCCCGCT | 84.8% | 88.6% |
| AACTGGCCCTCAAAGTCCCGCTT | 8.7% | 5.9% | |
| AACTGGCCCTCAAAGTCCCGCTA | 6.2% | 5.2% | |
| AACTGGCCCTCAAAGTCCCGCTG | 0.3% | 0.3% | |
| hsa-let-7a | TGAGGTAGTAGGTTGTATAGTT | 86.8% | 86.9% |
| TGAGGTAGTAGGTTGTATAGTTA | 9.3% | 9.2% | |
| TGAGGTAGTAGGTTGTATAGTTT | 3.6% | 3.5% | |
| TGAGGTAGTAGGTTGTATAGTTG | 0.4% | 0.3% | |
| hsa-miR-148a | TCAGTGCACTACAGAACTTTGT | 94.3% | 94.3% |
| TCAGTGCACTACAGAACTTTGTC | 3.9% | 3.6% | |
| TCAGTGCACTACAGAACTTTGTT | 1.3% | 1.4% | |
| TCAGTGCACTACAGAACTTTGTA | 0.5% | 0.7% |