Table 2 Representative IsomiRs detected in B-cells
From: Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing
miRNA | Sequence | % Control | % Centenarian |
|---|---|---|---|
hsa-miR-21 | TAGCTTATCAGACTGATGTTGAC | 53.8% | 52.0% |
| Â | TAGCTTATCAGACTGATGTTGA | 43.3% | 44.9% |
| Â | TAGCTTATCAGACTGATGTTGAA | 2.7% | 2.8% |
| Â | TAGCTTATCAGACTGATGTTGAT | 0.2% | 0.3% |
hsa-miR-193b | AACTGGCCCTCAAAGTCCCGCT | 84.8% | 88.6% |
| Â | AACTGGCCCTCAAAGTCCCGCTT | 8.7% | 5.9% |
| Â | AACTGGCCCTCAAAGTCCCGCTA | 6.2% | 5.2% |
| Â | AACTGGCCCTCAAAGTCCCGCTG | 0.3% | 0.3% |
hsa-let-7a | TGAGGTAGTAGGTTGTATAGTT | 86.8% | 86.9% |
| Â | TGAGGTAGTAGGTTGTATAGTTA | 9.3% | 9.2% |
| Â | TGAGGTAGTAGGTTGTATAGTTT | 3.6% | 3.5% |
| Â | TGAGGTAGTAGGTTGTATAGTTG | 0.4% | 0.3% |
hsa-miR-148a | TCAGTGCACTACAGAACTTTGT | 94.3% | 94.3% |
| Â | TCAGTGCACTACAGAACTTTGTC | 3.9% | 3.6% |
| Â | TCAGTGCACTACAGAACTTTGTT | 1.3% | 1.4% |
| Â | TCAGTGCACTACAGAACTTTGTA | 0.5% | 0.7% |