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Table 3 Summary statistics of qualified gene classifiers from network-specific searches

From: Discovery and validation of gene classifiers for endocrine-disrupting chemicals in zebrafish (danio rerio)

Chemical/tissue All tissues (495 search / condition)a Brain (496 search / condition) Ovary (495 search / condition) Testis (497 search / condition) Subtotal by chemical
Prochloraz & 177 68 76 321
Flutamide & NA 124 0 124
Fipronil & 71 17 20 108
17α-ethynyl estradiol 0 41 --- 50 91
Vinclozolin 0 NA 28 1 29
Ketoconazole & 18 7 --- 25
Muscimol & 22 --- NA 22
Fadrozole & 4 0 NA 4
17β-trenbolone & --- 0 NA  
trilostane 0 NA --- 0  
Subtotal by tissue   333 243 147  
  1. A total of 517 individual networks were analyzed by chemical-tissue conditions using genetic algorithm-K nearest neighbors. Within a condition, each TF network contributed one classifier composed of multiple gene features. “NA”, a condition not included in the study; “---“, insufficient sample size for classifier search; “0”, searched but no qualified classifier; “&”, no search conducted.
  2. aBetween 20 to 22 of the 517 networks did not contain sufficient number of genes to be searched due to variations in their availability in different datasets.