Table 1 Comparison of the differentially expressed genes in the S. mansoni -infected and the TNBS-treated ileum with candidate genes located within IBD susceptibility loci
Gene symbol | IBD type | S. mansoni-infected ileum | TNBS-treated ileum |
|---|---|---|---|
NOD2 | CD | ND | ND |
ATG16 | CD | ND | ND |
IRGM | CD | ND | ↓ |
LRRK2 | CD | ND | ND |
PTPN22 | CD | ND | ND |
CCR6 | CD | ND | ↓ |
IL-2RA | CD | ND | ND |
IL-18RAP | CD | ND | ND |
IL-27 | CD | ND | ND |
ERAP2 (Erap1/Eraap) | CD | ND | ND |
ITLN1 | CD | ND | ND |
CCL2 (Ccl12) | CD | ND | ND |
CCL7 | CD | ND | ND |
TNFSF11 | CD | ND | ND |
BACH2 | CD | ND | ND |
TAGAP | CD | ND | ND |
VAMP3 | CD | ND | ND |
DENNDIB | CD | ND | ND |
DNMT3A | CD | ND | ND |
GCKR | CD | ND | ND |
THADA | CD | ND | ND |
SP140 | CD | ND | ND |
PRDX5 | CD | ND | ND |
ZFP36L1 | CD | ND | ND |
ZMIZ1 | CD | ND | ND |
MUC1 | CD | ND | ND |
SCAMP3 | CD | ND | ND |
CPEB4 | CD | ND | ND |
FADS1 | CD | ND | ND |
SLC22A5 | CD | ND | ND |
ECM1 | UC | ND | ND |
HNF4A | UC | ND | ND |
CDH1 | UC | ND | ND |
LAMB1 | UC | ND | ND |
GNA12 | UC | ND | ND |
IFNG | UC | ND | ND |
IL-26 (Il-22) | UC | ND | ND |
IL-8RA/IL-8RB | UC | ND | ↑ |
IL-2 | UC | ND | ND |
IL-21 | UC | ND | ND |
IL-7R | UC | ND | ND |
TNFRSF9 | UC | ND | ND |
TNFRSF14 | UC | ND | ↓ |
FCGR2A (Fcgr3/Fcgr2b) | UC | ND | ND |
IRF5 | UC | ND | ND |
LSP1 | UC | ND | ND |
OTUD3 | UC | ND | ND |
PLA2G2E | UC | ND | ND |
DAP | UC | ND | ND |
PIM3 | UC | ND | ND |
CAPN10 | UC | ND | ND |
IL-23R | CD/UC | ND | ND |
IL-12B | CD/UC | ND | ND |
STAT3 | CD/UC | ND | ↑ |
AK2 | CD/UC | ND | ND |
TYK2 | CD/UC | ND | ND |
NKX2-3 | CD/UC | ND | ND |
CREM | CD/UC | ND | ND |
C11Orf30 (2210018M11Rik) | CD/UC | ND | ND |
ORMDL3 | CD/UC | ND | ND |
RTEL1 | CD/UC | ND | ND |
PTGER4 | CD/UC | ND | ↓ |
KIF21B | CD/UC | ND | ND |
CDKAL1 | CD/UC | ND | ND |
ZNF365 (Zfp365) | CD/UC | ND | ND |
HLA-DRB1 (H2-Eb1) | CD/UC | ND | ↓ |
MST1 | CD/UC | ND | ND |
IL-10 | CD/UC | ND | ↑ |
CARD9 | CD/UC | ND | ND |
REL | CD/UC | ND | ND |
PRDM1 | CD/UC | ND | ND |
TNFSF15 | CD/UC | ND | ND |
ICOSLG (Icosl) | CD/UC | ND | ND |
IL-1R2 | CD/UC | ND | ↑ |
YDJC (1810015A11Rik, Ccdc116) | CD/UC | ND | ND |
SMAD3 | CD/UC | ND | ND |
PTPN2 | CD/UC | ND | ND |