The regulatory effect of miRNAs is a heritable genetic trait in humans

BMC Genomics

Table 3 Top 10 associations for miRNA biogenesis pathway related SNPs (CEU)

	Location	Associated Gene	P-value	Bonferroni P	Q-value	Permutation
						p-value
rs17409624	chr5:31,528,733	DROSHA	1.81 × 10⁻⁰⁴	0.043	0.018	0.03
rs10078886	chr5:31,427,441	DROSHA	3.32 × 10⁻⁰⁴	0.079	0.018	0.051
rs16901121	chr5:31,418,215	DROSHA	3.32 × 10⁻⁰⁴	0.079	0.018	0.051
rs2279797	chr5:31,428,028	DROSHA	3.32 × 10⁻⁰⁴	0.079	0.018	0.051
rs13183642	chr5:31,511,106	DROSHA	1.25 × 10⁻⁰³	0.3	0.054	0.16
rs3805516	chr5:31,420,670	DROSHA	1.56 × 10⁻⁰³	0.37	0.056	0.2
rs4867349	chr5:31,536,327	DROSHA	1.82 × 10⁻⁰³	0.43	0.056	0.23
rs2287584	chr5:31,423,007	DROSHA	3.27 × 10⁻⁰³	0.78	0.073	0.33
rs615344	chr5:31,425,788	DROSHA	3.39 × 10⁻⁰³	0.8	0.073	0.34
rs682902	chr5:31,423,694	DROSHA	3.39 × 10⁻⁰³	0.8	0.073	0.34

The results for association of miRNA biogenesis pathway related SNPs with mean RE-score in the CEU.

ISSN: 1471-2164