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Table 2 The effect of SNPs on miRNA precursors energy change

From: Identification of common carp (Cyprinus carpio) microRNAs and microRNA-related SNPs

Precursor SNP position in precursor SNP SNP location G (kcal/mol)
s0008 19 A → C mature −0.3
s0027-1 53 U → G mature −1.4
s0008 39 C → G Stem 2.2
s0009 41 U → C Stem −0.5
s0015 48 C → A Stem 0.3
s0015 50 U → C Stem −1.3
s0027-1 52 G → U Stem 0.6
s0007 43 G → A Stem −0.1
mir-140 43 G → A Loop 0
s0007 39 A → C Loop 0
s0009 45 U → G Loop 0
s0013 40 C → U anti-stem 2.7
s0013 41 A → G anti-stem 1
  1. MFE: minimum free energy.
  2. ΔΔG: the MFE difference value between SNP-type precursors and wild-type precursors. The minus value indicated that the SNP-type precursors had lower structure energy than the wild precursors. Otherwise, the former had higher structure energy than the latter.