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Table 2 Comparison of expected and observed di-nucleotide frequencies and di-nucleotide PWM

From: Optimizing the GATA-3 position weight matrix to improve the identification of novel binding sites

 

1

2

3

4

5

AA

0

0

0

0

14

 

0

0

0

0

11.75

AT

0

0

72

0

10

 

0

0

71.04

0

5.88

AG

32

0

5

0

20

 

30.91

0

5.64

0

30.12

AC

0

0

0

0

4

 

0.46

0

0

0

2.2

TA

0

0

0

45

9

 

0

0

0

46.28

5.47

TT

0

0

1

24

0

 

0

0

1.08

21.53

2.73

TG

25

0

0

4

17

 

25.18

0

0.09

4.31

14.01

TC

0

0

0

1

0

 

0.38

0

0

1.08

1.03

GA

0

76

0

3

0

 

0

75.55

0

3.67

1.09

GT

0

1

1

2

0

 

0

1.14

1.08

1.71

0.55

GG

3

1

0

0

3

 

4.58

1.14

0.09

0.34

2.8

GC

1

0

0

0

1

 

0.07

0

0

0.09

0.21

CA

0

1

0

0

0

 

0

1.13

0

0

0.27

CT

0

0

0

0

0

 

0

0.02

0

0

0.14

CG

18

0

0

0

1

 

17.17

0.02

0

0

0.7

CC

0

0

0

0

0

 

0.26

0

0

0

0.05

AA

-4.62

-5.66

-6.16

-5.81

-0.16

AT

-4.14

-5.18

0.00

-5.33

-0.02

AG

0.00

-5.91

-3.39

-6.06

-0.05

AC

-4.41

-5.45

-5.94

-5.60

-1.20

TA

-4.02

-5.06

-5.55

0.00

0.00

TT

-4.58

-5.62

-4.72

-1.20

-4.17

TG

-0.09

-5.75

-6.24

-3.11

-0.06

TC

-4.69

-5.73

-6.22

-4.48

-4.27

GA

-4.69

0.00

-6.22

-3.38

-4.27

GT

-4.44

-4.08

-4.57

-3.54

-4.02

GG

-2.69

-4.83

-6.72

-6.38

-2.27

GC

-3.70

-6.14

-6.63

-6.29

-3.29

CA

-4.70

-4.34

-6.24

-5.89

-4.28

CT

-4.84

-5.89

-6.38

-6.04

-4.43

CG

-0.47

-5.80

-6.29

-5.95

-2.95

CC

-5.17

-6.22

-6.71

-6.37

-4.76

 

AG/TG/CG

GA

AT

TA

TA/AT/AG/TG/AA

  1. Optimized di- nucleotide frequency table and PWM. The observed frequencies are provided in the first line for each di-nucleotide, with the following line representing expected di-nucleotide frequencies (calculated from the mono-nucleotide frequencies). The presented are the frequencies of the di-nucleotides from the motifs selected from the interval -7 to 0.