Table 4 Performance of different PWMs in GATA-3 bound sequences and GATA-3 not bound sequences
From: Optimizing the GATA-3 position weight matrix to improve the identification of novel binding sites
PWM | GATA-3 bound sequences | GATA-3 not bound sequences | |||||
|---|---|---|---|---|---|---|---|
Total hits | TP sequences | FN | Sensitivity | Total hits | Total sequences with hits | TN | |
New-mono | 45095 | 21289 | 7040 | 75% | 39276 | 19760 | 8569 |
New-di | 58409 | 23378 | 4951 | 83% | 52897 | 22450 | 5879 |
Match_minFN | 102257 | 27158 | 1171 | 96% | 97461 | 27071 | 1258 |
Match_minFP | 673 | 663 | 27666 | 2.38% | 639 | 630 | 27699 |
Match_minSUM | 14988 | 11436 | 16893 | 43% | 12330 | 9846 | 18483 |