Transcriptomics in human blood incubation reveals the importance of oxidative stress response in Saccharomyces cerevisiae clinical strains

Table 1 Significant functional groups observed in up-regulated genes after 15, 30 and 60 min of incubation in blood for virulent (60, D14) and non-virulent (CECT 10431, W303) strains ^a

Functional groups	Time (min)
	15				30				60
	60	CECT 10431	W303	D14	60	CECT 10431	W303	D14	60	CECT 10431	W303	D14
Translation	+	+	-	+	+	+	-	+	+	+	-	+
Ribosome biogenesis	+	+	-	+	+	+	-	+	+	+	+	+
Gene expression	+	+	-	+	+	-	-	+	+	+	-	+
Amino acid biosynthetic process	+	-	-	-	+	+	-	+	+	+	-	+
Aspartate family amino acid biosynthetic process	-	-	-	-	+	+	-	+	+	-	-	-
Arginine biosynthetic process	-	-	-	-	+	+	-	+	+	-	-	-

^aFunctional groups were (+) or were not (−) significantly overrepresented (p-values < 0.05).

ISSN: 1471-2164