TY - JOUR AU - Norman, Joseph D. AU - Robinson, Mike AU - Glebe, Brian AU - Ferguson, Moira M. AU - Danzmann, Roy G. PY - 2012 DA - 2012/08/24 TI - Genomic arrangement of salinity tolerance QTLs in salmonids: A comparative analysis of Atlantic salmon (Salmo salar) with Arctic charr (Salvelinus alpinus) and rainbow trout (Oncorhynchus mykiss) JO - BMC Genomics SP - 420 VL - 13 IS - 1 AB - Quantitative trait locus (QTL) studies show that variation in salinity tolerance in Arctic charr and rainbow trout has a genetic basis, even though both these species have low to moderate salinity tolerance capacities. QTL were observed to localize to homologous linkage group segments within putative chromosomal regions possessing multiple candidate genes. We compared salinity tolerance QTL in rainbow trout and Arctic charr to those detected in a higher salinity tolerant species, Atlantic salmon. The highly derived karyotype of Atlantic salmon allows for the assessment of whether disparity in salinity tolerance in salmonids is associated with differences in genetic architecture. To facilitate these comparisons, we examined the genomic synteny patterns of key candidate genes in the other model teleost fishes that have experienced three whole-genome duplication (3R) events which preceded a fourth (4R) whole genome duplication event common to all salmonid species. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-13-420 DO - 10.1186/1471-2164-13-420 ID - Norman2012 ER -