Figure 2

Level of H3K9 and H3K14 acetylation correlates with magnitude of gene expression. A total of 12000 expressed genes in mES cells were divided into ten groups based on their expression levels, from the top 10% (blue, group 1) to the lowest 10% (purple, group 10). Mean tag densities of active histone marks; H3K9ac, H3K14ac, H3K4me3, H3K27ac and Pol II within (-/+) 3 kb are positively correlated with the transcription level of the genes. On the other hand, total H3 densities in the same regions are negatively correlated with the transcription level.