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Figure 8 | BMC Genomics

Figure 8

From: H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells

Figure 8

A subset of inactive promoters having high H3K14ac is poised for stimuli dependent activation. (A) Average ChIP-seq profile of 500 inactive genes around the transcription starts sites (-/+ 5 kb) shows specific enrichment of H3K14ac as opposed to H3K9ac. (B) Gene ontology (using David Bioinformatics,http://david.abcc.ncifcrf.gov/) analysis of 500 inactive genes having high H3K14ac suggest that these genes are activated in a stimuli dependent manner. The gene ontology term is on the y axis, and the negative log of p value indicating significance of enrichment is on the x axis.

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BMC Genomics

ISSN: 1471-2164

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