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Table 4 Expression values of genes encoding enzymes in ubiquitin-proteasome pathway at 15, 90 and 250 days of lactation

From: Transcriptional profiling of bovine milk using RNA sequencing

Protein Gene symbol1 Day 152 Day 902 Day 2502
UB activating enzyme (E1) UBA1 57.96 128.64 134.10
UB-conjugating enzyme (E2) CCDC34 0.32 1.14 1.47
  BRCA1 0.48 1.87 2.71
  UBE4B 5.83 9.83 13.01
  UBE4A 8.19 23.34 17.83
  UBE2R2 10.91 21.70 26.34
  UFD1L 27.59 45.93 39.23
  UBE2I 14.54 37.27 42.38
  UBE2C 6.43 19.54 42.98
  UBE2B 16.53 48.69 43.34
UB-protein ligase (E3) SKP2 0.24 1.00 1.07
  CUL5 0.93 1.80 2.39
  ANAPC10 1.63 3.12 3.05
  SMURF2 1.48 4.72 4.45
  CUL4B 3.02 4.87 5.29
  CUL2 1.62 6.14 5.96
  BTRC 2.11 12.92 6.21
  SMAD3 3.03 10.07 6.36
  ANAPC5 3.14 7.08 6.94
  ANAPC1 1.73 8.01 8.20
  CUL3 3.62 8.21 8.59
  CUL1 4.88 14.32 14.64
  FBXW2 9.39 27.72 25.13
  SMAD2 5.46 20.50 26.03
  CUL4A 15.25 59.93 44.91
  SKP1 14.72 61.88 48.03
  STUB1 42.41 55.86 52.47
  RBX1 33.24 42.01 76.38
UB and UB-like proteins SUMO1 0.88 0.70 1.15
  UBL7 49.97 18.95 22.41
  UBAP1 8.78 32.96 28.78
  NEDD8 50.89 98.49 106.18
  UBD 32.48 163.89 259.41
  UBC 112.33 1095.10 332.69
  RPS27A 551.89 451.18 630.29
  UBA52 1710.22 1277.97 1903.08
Deubiquitination enzymes USP2 0.60 0.37 0.23
  USP9X 0.05 0.46 0.56
  USP21 2.65 5.23 6.28
  VCPIP1 4.84 18.33 12.68
  USP8 4.54 10.15 14.05
  USP10 7.26 17.51 23.79
Proteasome ATAD2 0.66 3.37 2.39
  ATAD3A 8.23 13.67 11.38
  ATAD1 4.43 9.99 13.15
  PSMA1 18.19 49.89 69.91
  PSMD2 41.15 82.81 112.20
  PSMB2 39.62 84.58 115.62
  1. 1Gene symbol according to NCBI Entrez gene database http://www.ncbi.nlm.nih.gov/gene/
  2. 2Days 15, 90 and 250 gene expressions given in RPKM
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