Overview of a CTen session. CTen has been designed with a user-friendly interface to allow for rapid analysis of several gene lists, simultaneously. Panel (A) illustrates the workflow between the user, CTen interface and the HECS database. (B) At the upload screen, users can copy and paste their gene lists straight from spreadsheet software (e.g., Excel) and select the appropriate parameters (species, gene identifier and the separator used if multiple lists are being uploaded). (C) The data goes through preliminary processing to ensure the gene list(s) is parsed properly and that the supplied genes are found in the HECS database. Once the user list passes preliminary processing, the enrichment of all cell types in the HECS database is calculated.