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Table 2 Genes co-regulated with ANT1

From: Computational identification of transcriptionally co-regulated genes, validation with the four ANT isoform genes

Gene, ENSG ID Encoded protein (EnsEMBL) Protein function (UniProt)
ANO1 Anoctamin-1 Ca++-activated chloride channel, higher levels in liver and skeletal muscle
ARRDC3 Arrestin domain-containing protein 3 Associated with plasma membrane, highly expressed in skeletal muscle
ATP5B* ATP synthase, beta polypeptide H + transporting, mitochondrial F1 complex
ATP5D ATP synthase subunit δ, mitochondrial Mitochondrial membrane ATP synthase
ATP13A4 Cation-transporting ATPase 13A4 ATP + H2O = ADP + phosphate; expressed in heart, placenta, liver, skeletal muscles
CBY1* Protein chibby homolog 1 Expressed at higher levels in heart, skeletal muscle
COQ7* Ubiquinone biosynthesis protein COQ7 Involved in ubiquinone biosynthesis, expressed in heart and skeletal muscle
COX6B2* Cytochrome c oxidase subunit VIb 2 Connects the two mitochondrial COX monomers into the physiological form
COX7B* cytochrome c oxidase subunit VIIb One of the nuclear-coded polypeptide chains of cytochrome c oxidase
MYO1F* Myosin IF Myosins are actin-based motor molecules with ATPase activity
NDUFA9 NADH dehydrogenase 1 α- subcomplex, 9 Subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase
NDUFS1* NADH-ubiquinone oxido- reductase 75 kDa subunit Subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase
  1. Several constructed models of the ANT1 promoter region were screened as described in Figure 1 either on the full chromosomal human sequences or the human promoter library (results with an asterisk). Genes in bold are shown overexpressed in microarrays ( Additional file 3). Gene IDs are with 15 numbers (ex. ENSG00000023228).