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Table 4 Genes co-regulated with ANT4

From: Computational identification of transcriptionally co-regulated genes, validation with the four ANT isoform genes

Gene, ENSG ID Encoded protein (EnsEMBL) Protein function (UniProt)
AMDHD2 Acetylglucosamine-6-phosphate deacetylase N-acetyl-D-glucosamine 6-P + H2O = D-glucosamine 6-P + acetate
APEX1* APEX nuclease (DNA repair enzyme) 1 Repair of apurinic / apyrimidinic sites in testis
100823 §  
CDK4* cyclin-dependent kinase 4 Cell cycle G1 phase progression in male reproduction
135446 §  
CLPB* Caseinolytic peptidase B protein homolog Function as a regulatory ATPase and related to protein secretion
FIP1L1 Pre-mRNA 3'-end-processing factor FIP1 Contributes to poly(A) site recognition and poly(A) addition
FLJ32713 δ Unknown (TESTI2000756) Unknown (expressed in testis)
fis §  
FNDC3A* Fibronectin type-III domain-containing 3A Mediates spermatid-Sertoli adhesion during spermatogenesis
G6PC2* Glucose-6-phosphatase 2 Glucose production, expressed in testis
G6PC3* Glucose-6-phosphatase 3 Glucose production in endoplasmic reticulum, expressed in testis
KAT5* K(lysine) acetyltransferase 5 Chromatin remodelling with an abundant spermatid protein
172977 §  
KLHL12* Kelch-like protein 12 Ubiquitin-protein E3 ligase complex adapter, highly expressed in testis
LAMP1* lysosomal-associated membrane protein 1 Binds amelogenin, differentially expressed in spermiogenesis
185896 §  
RPUSD4* RNA pseudouridylate synthase domain-containing Unknown, expressed in prostate
165526 §  
SLC2A4 solute carrier family 2, member 4 (GLUT4) Facilitated glucose transporter, detected in human testis
181856 §  
SOHLH1 spermatogenesis and oogenesis specific HLH1 Germ cell-specific, oogenesis regulator and male germ cells
165643 §  
SUN1 chr. 7 unc-84 homolog A Nuclear anchorage/migration, expres- sion of meiotic reproductive genes
164828 §  
TDRD1* tudor domain containing 1 Essential for spermiogenesis
95627 §  
THAP8* O-sialoglycoprotein endopeptidase Unknown (TESTI2004929)
161277 §  
TKTL1 transketolase-like 1 Important role in transketolase activity, testis expressed
7350 §  
TMEM184A transmembrane protein 184A = Sdmg1 Male-specific expression in embryonic gonads
164855 §  
UBE2B* ubiquitin-conjugating enzyme E2B Post-replicative DNA damage repair in spermatogenesis
119048 §  
  1. Several constructed models of the ANT4 promoter region were screened as described in Figure 1 either on the full chromosomal human sequences or the human promoter library (results with an asterisk). Function involved in spermatogenesis or in testis or prostate metabolism is shown in bold characters. Genes in bold are shown overexpressed in microarrays ( Additional file 3). §Genes identified in the previous ModelInspector / GeneProm analysis [2]. δNo correct probe set on Affymetrix chips corresponding to this gene.