Table 1 Genome-wide hotspots of LXR action

R1

1

8412456-11763591

2

1

3

2

RP3-477M7.4, KIF1B, EXOSC10, RERE, ENO1

R3

1

23630263-26071982

2

2

3

1

RPL11, PNRC2, CLIC4, HNRNPR

R4

1

27018838-33511169

2

0

3

3

YTHDF2, SPOCD1, KHDRBS1, SLC9A1, PUM1, SNRNP40

R5

1

43282794-47844512

2

2

6

3

ERMAP, MED8, POMGNT1, KIAA0494, STIL, CMPK1, GPBP1L1, TMEM69, MKNK1

R6

1

150237798-154193105

1

2

8

2

MRPS21, MCL1, ENSA, GABPB2, S100A9, S100A8, RPS27, C1orf43, APH1A, PSMD4

R7

1

154934773-156706753

1

3

4

2

GON4L, KIAA0907, SLC25A44, CCT3, SHC1, C1orf66

R8

1

201798268-207228338

1

2

5

2

IPO9, UBE2T, KDM5B, TMEM183A, RBBP5, ADIPOR1, SOX13

R10

1

226626264-229694443

4

4

4

0

RP11-118H4.1, FTHL2, SPHAR, ABCB10

R14

2

69240275-73460367

0

2

5

2

ANTXR1, GFPT1, SNRNP27, MCEE, C2orf7, TEX261, RAB11FIP5

R20

3

127317065-129041381

1

1

1

2

CNBP, MCM2, C3orf37

R21

3

193585240-196669469

0

2

4

2

TM4SF19, AC092933.3, PAK2, NCBP2, TNK2, AC024937.4

R26

5

137273648-140086267

2

2

6

5

FAM13B, BRD8, ETF1, MATR3, PURA, C5orf53, EGR1, C5orf32, PFDN1, HARS, ZMAT2

R28

5

175818220-179780388

2

1

2

5

RP11-889L3.1, RNF130, PRELID1, HNRNPAB, RUFY1, CANX, GFPT2

R29

5

178977558-180671711

2

0

1

3

RNF130, RUFY1, CANX, GFPT2

R34

6

166778406-170893749

1

2

4

0

BRP44L, CCR6, PSMB1, PDCD2

R39

7

150069060-151361890

1

2

2

2

GIMAP8, FASTK, GIMAP5, AGAP3

R45

8

143354160-145736580

4

5

0

4

TOP1MT, PUF60, BOP1, MFSD3

R48

9

106856540-108403400

4

4

3

0

SMC2, ABCA1, FKTN

R51

9

138541640-140484943

7

9

1

2

EDF1, PMPCA, ZMYND19

R53

11

308106-911658

1

2

1

2

RPLP2, IFITM2, TMEM80

R56

11

63448921-66445276

5

4

2

8

TRMT112, PRDX5, RTN3, GPR137, DPF2, SSSCA1, FIBP, DPP3, RBM4, RBM4B

R57

11

66247879-70053509

1

2

1

4

FADD, DPP3, RBM4, RBM4B, SUV420H1

R59

11

118230301-126138751

1

2

5

6

UBE4A, AP000926.1, TMEM218, EI24, RPUSD4, ATP5L, ARCN1, HINFP, SLC37A2, FAM118B, SRPR

R61

12

56229243-57628892

2

1

5

4

AC034102.1, CNPY2, PTGES3, NACA, PRIM1, MMP19, RAB5B, RNF41,CS

R75

16

108057-2759032

1

4

4

3

STUB1, FAHD1, NDUFB10, PDPK1, RHBDF1, AC141586.5, KCTD5

R76

16

2009518-3072385

3

1

3

2

NDUFB10, PDPK1, TNFRSF12A, AC141586.5, KCTD5

R77

16

28616902-31394319

3

3

2

2

SULT1A1, VKORC1, QPRT, ITGAX

R80

17

3572089-7418491

3

0

5

1

TMEM93, ITGAE, MIS12, TXNDC17, ZBTB4, ACADVL

R83

17

41843489-47502285

2

1

7

4

DUSP3, GJC1, KIAA1267, KPNB1, PNPO, ZNF652, AC004797.1, NMT1, NSF, CDK5RAP3, NFE2L1

R84

17

55015562-59147703

2

2

3

4

COIL, SRSF1, AC005884.1, SUPT4H1, TRIM37, DHX40, TMEM49

R85

17

73512608-76377808

2

1

3

3

C17orf95, SRSF2, BIRC5, TSEN54, RHBDF2, SEC14L1

R86

17

78863340-80685893

5

4

4

5

ARL16, THOC4, SLC16A3, FN3KRP, AC127496.3, ACTG1, HGS, NARF, WDR45L

R93

19

17416476-19617122

3

0

2

2

PDE4C, C19orf50, MRPL34, RFXANK

R95

19

39109721-42789931

3

1

6

2

EIF3K, RPS16, EID2B, PSMC4, HNRNPUL1, RPS19, MRPS12, SERTAD3

R97

19

49298321-51303301

3

0

0

3

BCAT2, BAX, VRK3

R98

19

52359054-56499996

2

1

4

1

ZNF577, ZNF83, LILRB3, NLRP8, RPS9

R101

20

42939823-48809213

2

2

6

3

YWHAB, DNTTIP1, UBE2C, NCOA3, B4GALT5, RNF114, SERINC3, TMEM189-UBE2V1, CEBPB

R107

22

17618400-22901769

1

1

4

7

BID, PI4KA, RANBP1, AC002472.8, CECR5, ATP6V1E1, BCL2L13, COMT, C22orf25, XXbac-B33L19.3, PRAME

R108

22

22890122-25024973

2

0

1

2

MIF, PRAME, GGT1