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Table 2 LXR target genes with peaks in proximal region

From: Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages

Gene expression data

Peak within ± 100 kb

Peak within

100 kb-1 Mb

Chr

Start

P-value

Gene

FC

T09

vehicle

Heinz et al.

T09

vehicle

12

57094565

8.29E-05

NACA

5.63

S

L

 

S

S

15

69745123

1.88E-04

RPLP1

5.19

M

L

 

L

M

2

47272677

2.28E-04

CALM2

4.20

M

M

X

L

M

12

53689235

1.57E-04

PFDN5

3.59

S

M

 

L

L

5

177482390

9.93E-04

LOC653314

3.20

M

L

 

S

S

22

20103461

1.14E-04

RANBP1

3.17

S

M

 

M

M

9

107543283

4.46E-04

ABCA1

2.94

S

S

X

S

S

21

43619799

8.29E-05

ABCG1

2.87

S

S

X

L

M

11

9681985

3.86E-04

LOC731640

2.79

S

  

L

M

4

154073494

3.16E-04

TRIM2

2.75

M

M

 

M

M

11

64084167

6.49E-04

HSPC152

2.71

S

M

 

S

S

16

2009519

5.19E-04

NDUFB10

2.70

M

L

 

S

S

1

40306708

1.12E-04

TRIT1

2.44

M

M

 

M

M

19

41768391

4.25E-04

HNRPUL1

2.37

S

 

X

S

M

1

107599301

9.61E-05

PRMT6

2.25

M

M

   

16

50352941

1.44E-04

BRD7

2.20

M

M

X

 

L

9

128024073

5.65E-04

GAPVD1

2.02

M

M

 

M

M

6

16129356

1.63E-04

MYLIP

2.00

M

 

X

  

1

156163730

2.09E-04

SLC25A44

1.97

S

S

 

M

S

1

228823162

5.41E-04

FTHL2

1.92

S

S

 

S

S

5

137841784

7.92E-04

ETF1

1.91

S

S

 

L

M

11

9685628

5.87E-04

SWAP70

1.86

S

  

L

M

19

12907634

5.28E-04

PRDX2

1.84

S

L

X

L

S

12

57057127

4.78E-04

PTGES3

1.76

S

L

 

S

S

3

186507669

5.41E-04

RFC4

1.73

M

M

X

L

L

17

7362685

6.20E-04

ZBTB4

1.67

S

  

L

 

1

109852192

7.41E-04

SORT1

0.60

M

M

 

M

M

5

177631508

7.92E-04

HNRNPAB

0.59

S

S

 

M

M

9

137208944

8.64E-04

RXRA

0.56

M

M

 

S

M

3

57557090

9.67E-04

ARF4

0.55

S

  

L

M

11

62623518

1.88E-04

SLC3A2

0.43

S

L

 

S

S

  1. Only genes with a T09 peak with FDR < 1% within ± 100 kb from their TSS are displayed (the full list of LXR target genes is available in additional file 5: Table S2). Symbols for peaks are as follows: S = stringent peak with FDR < 1%, FE > 4 and P < 10-10; M = peak with FDR < 1%; L = peak with FDR < 5%; X = any peak.
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BMC Genomics

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