Analysis of TIR- and non-TIR-NBS-LRR disease resistance gene analogous in pepper: characterization, genetic variation, functional divergence and expression patterns

Table 5 Predicted specificity-determining residues of the non-TIR and TIR-NBS-LRR RGAs subfamilies in pepper

No.	Alignment position*	R gene group		Z-score	P-value**
		Non-TIR	TIR
1	91	W	D	4.72	2.41 × 10⁻⁴
2	98	W	Y	4.71	2.83 × 10⁻⁸
3	146	S	A	4.68	3.49 × 10⁻¹²
4	124	V	L	4.67	3.01 × 10⁻¹⁶

*Alignment position designates the amino acid position in the multiple sequence alignment presented in Additional file 3.
**P-value was used to evaluate the significance of the Z-score and assess whether the observed Z-score is sufficiently high to indicate an SDP.

ISSN: 1471-2164