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Table 3 Functional Annotation Enrichment analysis of statistically-significant over-expressed genes in European eel silver males from the river Tiber site (N = 8) in comparison with silver males from the lake Bolsena site (N = 7). FE = Fold Enrichment

From: Surviving in a toxic world: transcriptomics and gene expression profiling in response to environmental pollution in the critically endangered European eel

Category Term Count P value FE
KEGG_PATHWAY dre00052:Galactose metabolism 4 0.004 11.5
  dre00520:Amino sugar and nucleotide sugar metabolism 5 0.004 7.2
  dre00591:Linoleic acid metabolism 3 0.010 17.3
  dre00040:Pentose and glucuronate interconversions 3 0.016 13.8
  dre00511:Other glycan degradation 3 0.024 11.5
  dre00500:Starch and sucrose metabolism 3 0.042 8.7
  dre00980:Metabolism of xenobiotics by cytochrome P450 3 0.042 8.7
INTERPRO IPR002401:Cytochrome P450, E-class, group I 4 0.007 9.5
  IPR017973:Cytochrome P450, C-terminal region 4 0.009 8.8
  IPR017972:Cytochrome P450, conserved site 4 0.009 8.8
  IPR001128:Cytochrome P450 4 0.011 8.1
  IPR012335:Thioredoxin fold 5 0.041 3.7
SP_PIR_KEYWORDS heme 5 0.010 5.6
  monooxygenase 4 0.010 8.4
  oxidoreductase 8 0.023 2.7
GOTERM_BP GO:0055114 ~ oxidation reduction 11 0.005 2.7
  GO:0019882 ~ antigen processing and presentation 4 0.007 9.6
  GO:0006955 ~ immune response 4 0.042 5.0
GOTERM_MF GO:0009055 ~ electron carrier activity 7 0.013 3.5
  GO:0020037 ~ heme binding 5 0.025 4.3
  GO:0043167 ~ ion binding 27 0.037 1.4
  GO:0043169 ~ cation binding 27 0.037 1.4
  GO:0046906 ~ tetrapyrrole binding 5 0.039 3.8