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Figure 8 | BMC Genomics

Figure 8

From: Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR

Figure 8

Peak validation using Kolmogorov-Smirnov (KS) plot. The gene list for the LRH-1 ChIP-seq peaks that overlap with FXR ChIP-seq peaks was compared for their correlation to a set of genes that were activated by infection of primary mouse hepatocytes with a recombinant adenovirus expressing the constitutive FXRα2-VP16 hybrid protein as described in the text. Genes in the expression microarray were ranked by absolute fold change (A) or fold change (B) (x-axis) and the graph plots the running enrichment score.

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