Table 1 Summary results for the validated follicular lymphoma associated single-nucleotide polymorphisms
From: A meta-analysis of genome-wide association studies of follicular lymphoma
SNP | Gene(s) within 5 kb (hg18) | LOC (hg18) | A1/A2 | SF-NHL2 GWAS | SCALE GWAS | SF-NHL1 Validation | Combined meta-analysis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Logistic p-value | Logistic OR (95% CI) | MAF ca/co | Logistic p-value | Logistic OR (95% CI) | MAF ca/co | Logistic p-value | Logistic OR (95% CI) | MAF ca/co | P-value* | OR* (95% CI) | Q | I2 | ||||
rs9275517 | - | chr6 32782627 | A/G | 7.56E-04 | 0.67 (0.53- 0.85) | 0.29/0.38 | 6.73E-07 | 0.63 (0.53-0.76) | 0.37/0.48 | 2.32E-03 | 0.57 (0.39-0.82) | 0.29/0.41 | 4.03E-11 | 0.63 [0.55-0.73] | 0.7596 | 0% (0%-62.2%) |
rs3117222 | HLA-DPB1, Q30181 | chr6 33168927 | A/G | 4.17E-03 | 0.67 (0.51- 0.88) | 0.18/0.25 | 3.06E-04 | 0.68 (0.55-0.84) | 0.19/0.26 | 5.72E-03 | 0.58 (0.39-0.85) | 0.16/0.25 | 1.45E-07 | 0.66 [0.57-0.77] | 0.7673 | 0% [0%-60.7%] |