Skip to main content

Advertisement

Figure 5 | BMC Genomics

Figure 5

From: LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types

Figure 5

The percentage of PRC2 target vs. non-target genes harbouring significant (p-value<0.05) differential methylation. The significant differentially methylated genes from a select few developmental concepts including dermal, embryo, and neural development were subjected to further analysis with respect to PRC2 targets and the presence of CpG islands. As reported, a higher proportion of PRC2 target genes was differentially methylated in multiple tumor types. Interestingly, none of the PRC2 target genes involved in dermal development were differentially methylated in multiple myeloma.

Back to article page