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Table 1 Estimated coefficients of ribosome occupancy and ribosome density models

From: Bacterial translational regulations: high diversity between all mRNAs and major role in gene expression

Parameter

Variable to explain: Ribosome occupancy

Variable to explain: Ribosome density

mRNA concentration

0.12 (p = 1.2 x 10-4)

−0.15 (p = 4.0 x 10-6)

mRNA half-life

−0.38 (p < 2.0 x 10-16)

−0.36 (p < 2.0 x 10-16)

CDS length

0.24 (p = 2.3 x 10-14)

−0.22 (p = 1.4 x 10-10)

Aromaticity

/

0.09 (p = 8.7 x 10-3)

CAI

0.16 (p = 6.3 x 10-6)

−0.11 (p = 7.6 x 10-3)

ΔGdown

0.12 (p = 4.0 x 10-5)

0.12 (p = 3.0 x 10-4)

ΔGup

0.15 (p = 4.0 x 10-7)

0.15 (p = 5.7 x 10-6)

Functional category AMI

/

−0.20 (p = 5.0 x 10-3)

Functional category COF

/

−0.35 (p = 4.4 x 10-2)

Functional category INT

0.68 (p = 1.6 x 10-3)

/

Functional category REG

0.62 (p = 1.7 x 10-5)

0.45 (p = 3.9 x 10-3)

Functional category TRS

−0.23 (p = 4.0 x 10-2)

/

Adjusted R2

0.34

0.22

  1. ΔGdown and ΔGup: free energy of the predicted minimum free energy structure for upstream mRNA sequences (from −100 to +24 bp relative to the start codon) and downstream sequences (from −24 to +100 bp relative to the stop codon), respectively. AMI: amino acid biosynthesis, COF: biosynthesis of cofactors, INT: central intermediary metabolism, REG: regulatory functions, TRS: transcription.