Figure 4

Feature numbers for the core and pan-genome across 17 L . casei strains. Panel A shows numbers of total features in the core (blue) and pan-(red) genome as a function of the number of strains sequenced. The average of 500 random permutations of the genome order is presented for the pan and core genome content; the error bars represent the standard deviation of these results. The heat map in panel B illustrates the distribution of core and accessory genes (combined in red) across the 17 sequenced strains. New accessory genes that are contributed to the pan-genome by each strain's sequence are depicted as a red cap at the top of each strain name. Black regions under that cap indicate features missing in that strain but present in one or more of the other sequenced L. casei.