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Table 2 Genes a present in at least four of the pathways analyzed in Table 1, using gene and protein expression data together

From: Zonation related function and ubiquitination regulation in human hepatocellular carcinoma cells in dynamic vs. static culture conditions

   

Genes

    

Number of

 

μFB cultures

   

PD cultures

  

pathways

CYP3A43

CYP3A4

CYP3A7

     

6

POLD3

POLD2

       

ALDH3A2

ALDH2

   

BRAF

  

5

POLE2

POLE3

RPA2

MAPK3

MYC

PPP3CC

IL5

TGFB2

 

CYP1A1

  

EGFR

CACNA1C

CDC42

PDGFRA

CREBBP

4

   

PDGFB

RAP1A

PAK1

PRKCG

PPP3RR2

 
  1. a Genes in bold font code for HCC-related CYPs in the μFB group, and for kinases (or protein having kinase activity) in the PD group.