Overall proteome changes during development and Gene Ontology ( GO ) term enrichment. (A) Displayed are the fractions of proteins that change or remain unchanged in abundance during development. Additionally the direction of change is indicated (up/down). Figure corresponds to data shown in Table1. (B) GO term enrichment. Green indicates fraction of proteins ≥ 2x upregulated, red (≥ 2x downregulated) and orange (unchanged).